Protein Alignment mEFG1 and CG2017

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_649603.3
• Gene: CG2017 / 40733
• FlyBaseID: FBgn0037391
• Length: 643
• Species: Drosophila melanogaster
• Alignment Length: 667
• Identity: 136/667 - (20%)
• Similarity: 213/667 - (31%)
• Gaps: 247/667 - (37%)

  Fly     3 LIT----RLLTGNNTLRLRALKSLG--KAGY-------SSHAKFSEHKPIERIRNIGISAHIDSG 54
            |:|    ||..||.    .|:..:|  .|||       ..:|..:..|  :...::|.|..:...
  Fly   132 LVTQMKWRLREGNG----EAIYEIGVSDAGYLQGLSDKDMNASLTTLK--QMAHSLGASTSVLRR 190

  Fly    55 KTTLTERILFYTGRIAEM---------H--EVR---------GKDNVGATMDSMELERQRGIT-- 97
            ||....|      .:||:         |  |||         ||..:...:...||:...|..
  Fly   191 KTIAARR------AVAEVLVRKIPDDQHNIEVRVAVLGGADAGKSTLLGVLTQDELDNGHGRARL 249

  Fly    98 --------IQSAAT-----YTLWKDTNINIIDTPGHVDFTVE--VERALRVLDGAVLVLCAVGGV 147
                    |||..|     .||..|...|:::...:...|.|  .:|:.::             |
  Fly   250 NMFRHMHEIQSGRTSCISHETLGFDALGNVVNYKYNEMMTAEEISDRSSKL-------------V 301

  Fly   148 QSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVD 212
            ....|..:|:..|..|..|:        |.:|:               :..|.:...|.|....:
  Fly   302 TFMDLAGHRRYMRTTVQALS--------GYSPH---------------YAMLVVSAGSGCNDTTE 343

  Fly   213 LVREKAIYFEGEHGMDIRLDEIPQDMRV--ESLERRQELIEHLSNADETLGELFLEEKPF----T 271
                       ||...:|..::|..:.|  ..:......::.|.|...|:|   ..:.||    |
  Fly   344 -----------EHLAIVRALDMPFFVLVTKTDITSPDATVQELCNLLTTIG---CRKVPFVVTNT 394

  Fly   272 EDDIKAALRRTCINRTFTPV-----LVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQD 331
            ::.|.|...:  |:....|:     :.||.|.      |:...| |:.:|| :.|   .||:..:
  Fly   395 DEAISAGSNQ--ISENIVPIFCVSNVTGTGLN------LVTKFL-YVLSPG-ISN---AEKDRLE 446

  Fly   332 PEKVVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLH 396
            .|.                                |...|    |.||
  Fly   447 QES--------------------------------CEFQV----DEIF----------------- 458

  Fly   397 SNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLSMESIFVPE----PVVSMAIKPNNTKDR 457
              ::.||..|..|  ..:.||           ...|::|:...:|:    ||....|..|
  Fly   459 --RVSDVGPVVGG--LLVQGV-----------LTENMAMKIGPLPDGSFHPVTVNTIHRN----- 503

  Fly   458 DNFSKAIARFTK--EDPTFHFFFDNDVKETLVSGM---GELHLEIYAQRMEREYGCPVTLGKPKV 517
                ||..|..:  :..:..|..|.|| .||.|||   |::     ...::..||......|..|
  Fly   504 ----KAPCRVVRAGQSASLSFSMDQDV-PTLRSGMVLLGDI-----GNSLDEPYGTFFFQAKVSV 558

  Fly   518 AFRETLVGPCEFDYLHKKQS---GGSGQYARIIGVM--EPLPPNQ--NTLLEFVDETVGTNVPKQ 575
            .|..|.:      |:..:.:   |...|.|.|.|:|  |.|..|.  :.:.|||..      |:.
  Fly   559 LFHATAI------YVGFQTTVHIGSIRQTAVIRGIMGGERLGTNDCASVMFEFVGH------PEY 611

  Fly   576 FVPGVEKGYREMAEKGM 592
            ..||:...:||...||:
  Fly   612 VRPGMRILFREGTSKGI 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	123/619 (20%)
CG2017	NP_649603.3	GTPBP1_like	217..436	CDD:206728	50/277 (18%)
		GTPBP_II	450..536	CDD:293895	30/131 (23%)
		GTPBP_III	547..634	CDD:294007	26/94 (28%)