DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mEFG1 and Dgp-1

DIOPT Version :9

Sequence 1:	NP_609105.1	Gene:	mEFG1 / 34004	FlyBaseID:	FBgn0263133	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_611302.1	Gene:	Dgp-1 / 37080	FlyBaseID:	FBgn0027836	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	77/347 - (22%)
Similarity:	130/347 - (37%)	Gaps:	70/347 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLTGN---NTLRLRALKSLGKAGYSSHAKFSEHKPIE-----RIRNIGISAHIDSGKTTLTERIL 63
            ||..|   :.::||..::  :.|.|  |:|...|.|:     .|| :.:..::|:||:||. .:|
  Fly   105 LLAANIDADVVKLRERRA--EKGQS--AQFLIRKHIDTTDFMEIR-VAVVGNVDAGKSTLL-GVL 163

  Fly    64 FYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTP--GHVDFTVE 126
            .:    .|:...||...........|:|..|   ..|.....|..|...|:::.|  ||:|:...
  Fly   164 TH----GELDNGRGHARQRLFRHKHEIESGR---TSSVGNDILGFDGVGNVVNKPDHGHLDWVKI 221

  Fly   127 VERALRVL------------------------DGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLA 167
            .|.:.:|:                        |..:|::.|..|:...|...........||...
  Fly   222 CENSAKVITFIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGIIGMTKEHLGLALALAVPVFV 286

  Fly   168 FINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLD 232
            .:.|:|...:|..:...::..||..:....::|:.|.|:     |.|...|..|..|     ||.
  Fly   287 VVTKIDMCPANVLQENMKLLFKMLKSQGCRKVPVVVRSH-----DDVVLSATNFVSE-----RLC 341

  Fly   233 EIPQDMRV--ESLERRQELIEHLSN---ADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVL 292
            .|.|...|  ::||..:..:..||.   ..|:|...|..:..:....:...:..||        |
  Fly   342 PIFQVSNVTGDNLELLKMFLNLLSTRMPGSESLPAEFQIDDVYAVPGVGTVVSGTC--------L 398

  Fly   293 VGTALKNKGVQPLLDAVLDYLP 314
            .||...|..:....|||..::|
  Fly   399 QGTIRLNDCLMLGPDAVGSFVP 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	EF-G	44..316	CDD:206673	64/302 (21%)
		PRK12740	48..727	CDD:237186	64/298 (21%)
		mtEFG1_II_like	347..427	CDD:293908
		EFG_III	441..516	CDD:293919
		EFG_mtEFG1_IV	519..636	CDD:238715
		mtEFG1_C	641..718	CDD:239764
Dgp-1	NP_611302.1	GTPBP1	38..555	CDD:227583	77/347 (22%)
		GTPBP1_like	145..367	CDD:206728	52/240 (22%)
		GTPBP_II	376..462	CDD:293895	11/53 (21%)
		GTPBP_III	468..553	CDD:294007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464678
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930