Protein Alignment mEFG1 and eef2l2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_697966.6
• Gene: eef2l2 / 336168
• ZFINID: ZDB-GENE-030131-8112
• Length: 861
• Species: Danio rerio
• Alignment Length: 888
• Identity: 213/888 - (23%)
• Similarity: 342/888 - (38%)
• Gaps: 249/888 - (28%)

  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGAT--MDSMELERQRGITIQSAAT- 103
            |||:.:.||:|.||:|||:.::...|.||..       ..|.|  .|:.:.|::|.|||:|.|.
Zfish    19 IRNMSVIAHVDHGKSTLTDSLVCKAGIIASA-------RAGETRFTDTRKDEQERCITIKSTAIS 76

  Fly   104 --YTLWKDTN-------------INIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLT 153
              |.|.::.:             ||:||:||||||:.||..||||.|||::|:..|.||..||.|
Zfish    77 LYYELSENDSAFIKQCKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141

  Fly   154 VNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKA 218
            |.||.....:..:..:||:||                    |.::|.:..:...:....:|....
Zfish   142 VLRQAIAERIKPVLMMNKMDR--------------------ALLELQLEPDELFQTFQRIVENVN 186

  Fly   219 I----YFEGEHGM-----------------------------------------DIRLDEIPQDM 238
            :    |.|||||.                                         |.:..::|...
Zfish   187 VIISTYGEGEHGPMGNIMVDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGDKKKGDLPPTE 251

  Fly   239 RVESLERRQELIEHL-----------------SNAD-----ETLGELFLEE--------KPFTED 273
            |.:.:|   |:::.|                 :|||     .|..:|.|:.        ..|.::
Zfish   252 RAKKVE---EMMKKLWGDKYFDPSCGKFSKTANNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKE 313

  Fly   274 DIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLD---------------YLPNPGEVENLG 323
            :.:..:.:       ..|.:....|.|..:|||.||:.               :||:|...:...
Zfish   314 ETQKLIEK-------LEVKLDAEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQRYR 371

  Fly   324 ---FIEKEGQDPEKVVLNPARDGKDPFVGLAFKL----EAGRFGQLTYLRCYQGVLRKGDNIF-- 379
               ..|..|.|...:.:... |.|.|.:....|:    :.|||  ..:.|.:.|::..|..:.
Zfish   372 CELLYEGPGDDEAAMGIKNC-DPKAPLMMYISKMVPTTDKGRF--YAFGRVFSGIVSTGQKVRIM 433

  Fly   380 --NARTNKK-----VRIARLVRLHSNQMEDVNEVYAGDIFALFGVD--CASGDTFTT--NPKNNL 433
              |....||     ..|.|.:.:....:|.:.:|..|:|..|.|||  .....|.||  |..|..
Zfish   434 GPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFENSHNMR 498

  Fly   434 SMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIY 498
            .|:  |...|||.:|::..|..|.....:.:.|..|.||......: :..|.:|:|.|||||||.
Zfish   499 VMK--FSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIE-ESGEHIVAGAGELHLEIC 560

  Fly   499 AQRMEREYGC-PVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQY------------------- 543
            .:.:|.::.| |:....|.|::|||:....:...|.|..:..:..|
Zfish   561 LKDLEEDHACIPLKKSDPVVSYRETVSDESDQVCLSKSPNKHNRLYMKSRPFPDGLAEDIDKGDV 625

  Fly   544 -----------------------ARIIGVMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYR 585
                                   ||.|....|.....|.|   ||.|.|.....:....|..|::
Zfish   626 SSRQELKLRARYLAEKYEWEVAEARKIWCFGPDGTGPNIL---VDITKGVQYLNEIKDSVVAGFQ 687

  Fly   586 EMAEKGMLSGHKLSGIRFRLQD----------GGHHIVDSSE---LAFMLAAHGAIKEVFQNGSW 637
            ...::|.|....:..:||.:.|          ||..|:.::.   .|.:|.|..
Zfish   688 WATKEGALCEENMRAVRFDIHDVTLHADAIHRGGGQIIPTARRVLYASVLTAQP----------- 741

  Fly   638 QILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGW--FTVYAEVPLNDMFGYAGELRSS 700
            :::|||.|||:..||:..|.:.|.|:::.|.:.......|.  |.|.|.:|:|:.||:..:|||:
Zfish   742 RLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPIFVVKAYLPVNESFGFTADLRSN 806

  Fly   701 TQGKG--EFTMEYSRYSPCLP-DVQ---DQIVRQYQESQGLAQ 737
            |.|:.  :...::.:..|..| ||.   .|||...::.:||.:
Zfish   807 TGGQAFPQCVFDHWQILPGDPYDVNSKPSQIVADTRKRKGLKE 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	211/880 (24%)
eef2l2	XP_697966.6	None