Protein Alignment mEFG1 and eef2b

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_956752.2
• Gene: eef2b / 326929
• ZFINID: ZDB-GENE-030131-5128
• Length: 858
• Species: Danio rerio
• Alignment Length: 871
• Identity: 211/871 - (24%)
• Similarity: 335/871 - (38%)
• Gaps: 218/871 - (25%)

  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGAT--MDSMELERQRGITIQSAATY 104
            |||:.:.||:|.||:|||:.::...|.||..       ..|.|  .|:.:.|::|.|||:|.|..
Zfish    19 IRNMSVIAHVDHGKSTLTDSLVSKAGIIASA-------RAGETRFTDTRKDEQERCITIKSTAIS 76

  Fly   105 TLWKDTN----------------INIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLT 153
            ..::.|.                ||:||:||||||:.||..||||.|||::|:..|.||..||.|
Zfish    77 MYYELTENDLAFIKQCKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141

  Fly   154 VNRQMKRYNVPCLAFINKLDR----LGSNPYRVLSQMRSKMNHNAAFIQLPIGV-ESNCKG--IV 211
            |.||.....:..:..:||:||    |...| ..|.|...::..|...|....|. |....|  ::
Zfish   142 VLRQAIAERIKPVLMMNKMDRALLELQLEP-EELYQTFQRIVENVNVIISTYGEDEGGPMGNIMI 205

  Fly   212 DLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNAD------------------- 257
            |.|.....:..|.||....|.:. .:|.|.....:.|  ..||.||
Zfish   206 DPVIGTVGFGSGLHGWAFTLKQF-AEMYVAKFASKGE--AQLSPADRCKKVEDMMKKLWGDRYFD 267

  Fly   258 -------------------ETLGELFLEE--------KPFTEDDIKAALRRTCINRTFTPVLVGT 295
                               .|..:|.|:.        ..|.:::....:.:..|.       :.|
Zfish   268 PAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLIEKLDIK-------LDT 325

  Fly   296 ALKNKGVQPLLDAVLD---------------YLPNPGEVENLG---FIEKEGQDPEKVVLNPARD 342
            ..|:|..:|||.||:.               :||:|...:...   ..|..|.|...:.:... |
Zfish   326 EDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEAAMGIKNC-D 389

  Fly   343 GKDPFVGLAFKL----EAGRFGQLTYLRCYQGVLRKGDNIF----NARTNKK-----VRIARLVR 394
            .|.|.:....|:    :.|||  ..:.|.:.||:..|..:.    |....||     ..|.|.:.
Zfish   390 PKGPLMMYISKMVPTTDKGRF--YAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTIL 452

  Fly   395 LHSNQMEDVNEVYAGDIFALFGVD---CASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKD 456
            :....:|.:.:|..|:|..|.|||   ..:|...|.:..:|:.:.. |...|||.:|::..|..|
Zfish   453 MMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMK-FSVSPVVRVAVEAKNPAD 516

  Fly   457 RDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGC-PVTLGKPKVAFR 520
            .....:.:.|..|.||......: :..|.:::|.|||||||..:.:|.::.| |:....|.|::|
Zfish   517 LPKLVEGLKRLAKSDPMVQCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYR 580

  Fly   521 ETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLP------------------------------- 554
            ||:  ..|.|.:...:|  ..::.|:.....|.|
Zfish   581 ETV--SAESDQMCLSKS--PNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEW 641

  Fly   555 -----------------PNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIR 602
                             ||.     .||.|.|.....:....|..|::...::|.|....:..:|
Zfish   642 EVTEARKIWCFGPDGTGPNM-----LVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVR 701

  Fly   603 FRLQD----------GGHHIVDSSE---LAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEF 654
            |.:.|          ||..|:.::.   .|..|.|..           :::|||.|||:..||:.
Zfish   702 FDIHDVTLHTDAIHRGGGQIIPTARRVLYACQLTAEP-----------RLMEPIYLVEIQCPEQV 755

  Fly   655 QGAVMGHLSKRHGIITGTEGTEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPC 717
            .|.:.|.|:::.|.:.......|  .|.|.|.:|:|:.||:..:|||:|.|:......:..:...
Zfish   756 VGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQIL 820

  Fly   718 LPDVQD------QIVRQYQESQGLAQ 737
            ..|.:|      |||...::.:||.:
Zfish   821 PGDPKDAASKPCQIVADTRKRKGLKE 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	209/863 (24%)
eef2b	NP_956752.2	PTZ00416	1..858	CDD:240409	211/871 (24%)