Protein Alignment mEFG1 and mef2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_595089.1
• Gene: mef2 / 2541108
• PomBaseID: SPBC660.10
• Length: 813
• Species: Schizosaccharomyces pombe
• Alignment Length: 807
• Identity: 249/807 - (30%)
• Similarity: 382/807 - (47%)
• Gaps: 167/807 - (20%)

  Fly    32 KFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGI 96
            ::..:..|..|||:||.||||:|||||||::|:|.|..:....|...|.|   ||.:..||||||
pombe    18 RYQSNISINSIRNVGIIAHIDAGKTTLTEKMLYYGGFTSHFGNVDTGDTV---MDYLPAERQRGI 79

  Fly    97 TIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRY 161
            ||.|||....|::..||:||||||.|||.||||::.||||||.::....||::||..|.:|..:.
pombe    80 TINSAAISFTWRNQRINLIDTPGHADFTFEVERSVAVLDGAVAIIDGSAGVEAQTKVVWKQATKR 144

  Fly   162 NVPCLAFINKLDRLGSN--------------PYRVLSQMRSKMNHNAAFIQLPI---GV-ESNCK 208
            .:|.:.|:||:||:||:              ||.::             :|||:   |: |....
pombe   145 GIPKVIFVNKMDRVGSSLGSTIRSIYTNLDCPYPLV-------------LQLPVYSDGLQERKFL 196

  Fly   209 GIVDLVREKAIYFE------GEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEE 267
            ||:|::::|.|.::      |..|..::...||:......:|.|..|:..|.:.||||.:.:||.
pombe   197 GILDILQQKMILWDTSDNKLGTDGTHVQELPIPESHMERFIEARNALVMSLCDVDETLCDEYLEN 261

  Fly   268 K---PFTEDDIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEG 329
            :   .||.|.:...:::..|:....|||.|::|||..|||::||::||||:|.|     |.||..
pombe   262 EDSLAFTNDRLFKIIKQKTISGNVVPVLCGSSLKNIAVQPIMDAIIDYLPSPVE-----FYEKNA 321

  Fly   330 Q---DPEKVVLNPARDGKDPFVGLAFKL--EAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRI 389
            .   ..:|::   :.| |.|.:...||:  .|.| |.|||:|..:|.|.:|..:||.||.|..|.
pombe   322 SKETSSDKII---SLD-KRPLLAKIFKVIHHASR-GILTYVRVNEGTLSRGMMMFNPRTKKSERA 381

  Fly   390 ARLVRLHSNQMEDVNEVYAGDIFALFGV-DCASGDTFTT--NPKN-------NLSMESIFVPEPV 444
            .||..:.::|.::|:.:.||:|..:.|: ...:||....  |.||       |.|:  |.:||||
pombe   382 IRLYNVFADQTQEVDCISAGNIGVISGIKQFHTGDIIINKENSKNFHEYLSGNQSV--ISIPEPV 444

  Fly   445 VSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCP 509
            ...:|:|.:.||.....:|:|...:|||:|.:..|.:..:.|:.|||.:||::..:|:..|:|..
pombe   445 CIASIEPYSLKDEPALLEALANMNREDPSFRYTQDLENGQLLIQGMGIMHLQVSYERLVSEFGAR 509

  Fly   510 VTLGKPKVAFRETLVGPC-------------------------EFDYLHKKQ-SGGSGQYARIIG 548
            .:|||.:|.:||||:...                         |.|...||. |.|..|..|..|
pombe   510 ASLGKVQVGYRETLIDVSFNSVTLSTENKENLIINVYLIPISDEGDETLKKYFSEGEIQKVRSKG 574

  Fly   549 VMEPL------PPNQNTLLEFVD-ETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIR---- 602
            ..:.:      |.|..||.:.:. :.:..|:....|.|:        ..|.|.|..|:.::
pombe   575 QEDGVLFYGWKPENSCTLPDHLSFQRIQENIYFGIVAGL--------SHGPLHGFPLTNLQSFCT 631

  Fly   603 ---FRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNG--SWQILEPIMLVEVTAPEEFQGAVMGHL 662
               |...|....::..   |.|.|...|:..:::..  |::||||.|.|.:|.|||:.|.|...|
pombe   632 ISSFLSNDFPLSLLTQ---ASMKATKNAVFSLYKRSPKSFRILEPYMDVTITTPEEYVGIVSKDL 693

  Fly   663 -------------------SKRHGIITGTEGTEGWF------------------------TVYAE 684
                               ||...|..|..| |.:.                        .:.|:
pombe   694 VGKRGATIKEITEIGKNAASKDSQIAIGILG-ERYLPADEPSSVKANNASSLLQSSSVIKCIRAQ 757

  Fly   685 VPLNDMFGYAGELRSSTQGKGEFTMEY 711
            |||..:..|...:.|.|:|..:|.|.:
pombe   758 VPLEQILDYNSVISSLTKGNAKFLMSH 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	249/801 (31%)
mef2	NP_595089.1	FusA	21..784	CDD:440248	249/802 (31%)