Protein Alignment mEFG1 and Eef2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_031933.1
• Gene: Eef2 / 13629
• MGIID: 95288
• Length: 858
• Species: Mus musculus
• Alignment Length: 858
• Identity: 209/858 - (24%)
• Similarity: 345/858 - (40%)
• Gaps: 191/858 - (22%)

  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGAT--MDSMELERQRGITIQSAATY 104
            |||:.:.||:|.||:|||:.::...|.||..       ..|.|  .|:.:.|::|.|||:|.|..
Mouse    19 IRNMSVIAHVDHGKSTLTDSLVCKAGIIASA-------RAGETRFTDTRKDEQERCITIKSTAIS 76

  Fly   105 TLWK----DTN------------INIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLT 153
            ..::    |.|            ||:||:||||||:.||..||||.|||::|:..|.||..||.|
Mouse    77 LFYELSENDLNFIKQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141

  Fly   154 VNRQMKRYNVPCLAFINKLDR----LGSNPYRVLSQMRSKMNHNAAFIQLPIGV-ESNCKG--IV 211
            |.||.....:..:..:||:||    |...| ..|.|...::..|...|....|. ||...|  ::
Mouse   142 VLRQAIAERIKPVLMMNKMDRALLELQLEP-EELYQTFQRIVENVNVIISTYGEGESGPMGNIMI 205

  Fly   212 DLVREKAIYFEGEHGMDIRLDEIPQ----------DMRVESLERRQELIEHLSNADETLGELFLE 266
            |.|.....:..|.||....|.:..:          :.::.:.||.:::.:.:.   :..|:.:.:
Mouse   206 DPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLSAAERAKKVEDMMK---KLWGDRYFD 267

  Fly   267 ------EKPFTEDDIKAALRRTC------INRTFTPVL-----------------VGTALKNKGV 302
                  .|.....|.|...|..|      |.:.|..::                 :.:..|:|..
Mouse   268 PANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDIKLDSEDKDKEG 332

  Fly   303 QPLLDAVLD---------------YLPNP--GEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGL 350
            :|||.||:.               :||:|  .:......:.:...|.|..:...:.|.|.|.:..
Mouse   333 KPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMY 397

  Fly   351 AFKL----EAGRFGQLTYLRCYQGVLRKGDNIF----NARTNKK-----VRIARLVRLHSNQMED 402
            ..|:    :.|||  ..:.|.:.||:..|..:.    |....||     ..|.|.:.:....:|.
Mouse   398 ISKMVPTSDKGRF--YAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEP 460

  Fly   403 VNEVYAGDIFALFGVD---CASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAI 464
            :.:|..|:|..|.|||   ..:|...|....:|:.:.. |...|||.:|::..|..|.....:.:
Mouse   461 IEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMK-FSVSPVVRVAVEAKNPADLPKLVEGL 524

  Fly   465 ARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGC-PVTLGKPKVAFRETLVGPCE 528
            .|..|.||......: :..|.:::|.|||||||..:.:|.::.| |:....|.|::|||:.....
Mouse   525 KRLAKSDPMVQCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESN 588

  Fly   529 FDYLHKKQSGGSGQYARI---------------IGVMEPLPPNQNTLLE--------------FV 564
            ...|.|..:..:..|.:.               :...:.|......|.|              |.
Mouse   589 VLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFG 653

  Fly   565 DETVGTNVPKQFVPGVE----------KGYREMAEKGMLSGHKLSGIRFRLQD----------GG 609
            .:..|.|:......||:          .|::...::|.|....:.|:||.:.|          ||
Mouse   654 PDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGG 718

  Fly   610 HHIVDSSE---LAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITG 671
            ..|:.::.   .|.:|.|..           :::|||.|||:..||:..|.:.|.|:::.|.:..
Mouse   719 GQIIPTARRCLYASVLTAQP-----------RLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFE 772

  Fly   672 TEGTEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPD-----VQDQIVRQY 729
            .....|  .|.|.|.:|:|:.||:..:|||:|.|:.        :..|:.|     ..|......
Mouse   773 ESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQA--------FPQCVFDHWQILPGDPFDNSS 829

  Fly   730 QESQGLAQPDKKK 742
            :.||.:|:..|:|
Mouse   830 RPSQVVAETRKRK 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	204/845 (24%)
Eef2	NP_031933.1	PTZ00416	1..858	CDD:240409	209/858 (24%)