Protein Alignment mEFG1 and mRRF2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_061516391.1
• Gene: mRRF2 / 1278061
• VectorBaseID: AGAMI1_001775
• Length: 750
• Species: Anopheles gambiae
• Alignment Length: 767
• Identity: 224/767 - (29%)
• Similarity: 373/767 - (48%)
• Gaps: 92/767 - (11%)

  Fly    15 RLRALKSLGKAGYSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKD 79
            ||.|..:..:..::|....||    :|||||||.||||:||||.|||:|:|:||...:.||:
Mosquito    18 RLPATVASCRQVHNSDGTISE----KRIRNIGILAHIDAGKTTTTERMLYYSGRTDMLGEVK--- 75

  Fly    80 NVGATM-DSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCA 143
             :|.|: |.::.||:|||||.|||....||:..||::|||||:|||:|||::|..:||.|::|..
Mosquito    76 -LGNTVTDFLQQERERGITICSAAVSFNWKEYRINLLDTPGHIDFTMEVEQSLGAVDGTVIILDG 139

  Fly   144 VGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCK 208
            ..||::||:||..|..|:.:|.|.|:||:|:..::....|..:..|::.....:|:||.......
Mosquito   140 SAGVEAQTVTVWGQADRHRLPRLVFVNKMDKESADFDACLEDLEKKLSTVPVPLQMPIKEAGKLV 204

  Fly   209 GIVDLVREKAIYFEGEHGMDIRLDEIP---QDMRVESLERRQELIEHLSNADETLGELFLEEKPF 270
            |::|::....|.::.: |.......||   :.:..:..|:..|||:.||..|:.|.:..:|....
Mosquito   205 GVIDVLSASQIIWDSK-GKGRSYKAIPISDEQLHDQVQEKLYELIDLLSGMDDNLAQAIIEANSL 268

  Fly   271 TEDDIKA-----ALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQ 330
              :::|.     |||...:.:...|||:|::.||.|||.|:|:||::||.|.|
Mosquito   269 --ENVKLNLVLDALRNCTLKQQIVPVLLGSSYKNVGVQLLMDSVLNFLPAPSE------------ 319

  Fly   331 DPEKVVLNPARD--GKDPFVGLAFKLEAGR-FGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARL 392
                  .|...|  |.| |||..||:...: .|.:|.:|.::|.::||.....| |.....|.|:
Mosquito   320 ------RNQIYDCFGND-FVGKVFKVTHDKQRGPITMIRAFRGTVKKGSKFITA-TGGSETIQRI 376

  Fly   393 VRLHSNQMEDVNEVYAGDIFALFG-VDCASGDTFTTNP--------------------------- 429
            ....:::..::....||:|....| ....:||....|.
Mosquito   377 YEPLADEYREIESFGAGNIGLCAGPKSTVTGDLVVANAAALKKALKRLSTASDSTDESADDELLL 441

  Fly   430 KNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELH 494
            .:.|.:::. :|:.|...:|:|.::..:.....|:....:|||:....:|....:|::.|||:||
Mosquito   442 ASKLGLQTT-IPDAVYFCSIEPPSSGQQSALDNALREIQREDPSLRVRYDEVTGQTVLGGMGQLH 505

  Fly   495 LEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNT 559
            |||...|:..||.....||..::|::|||..||..::..:|:..||.|...:...:.|...:::.
Mosquito   506 LEIVKSRILTEYRIDADLGPLQIAYKETLDEPCRGEWRAEKEIAGSKQSVYMDMTIHPSTASESN 570

  Fly   560 LLEFV-------DETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSE 617
            ....|       .||:....|:| :....||.....::|...|.:|:....:|    |.:.....
Mosquito   571 EERIVLDNSAEAQETLKLVRPRQ-MTFFRKGALAALQRGPKLGGQLANCTIKL----HALTIGKG 630

  Fly   618 LA--FMLAAHG-AIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGII--TGTEGTEG 677
            .|  |::||.. .|..:..|...::|||.|.:|:..|.|:...::..||:|...|  ....|:..
Mosquito   631 TADPFIMAASAQCIGNILANARCRLLEPDMFLEIVTPSEYLPPILADLSRRRARIEDVAPRGSAN 695

  Fly   678 -WFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQ 728
             ..||.|  ||.::..|:..||:.:.|....:||.:.:||.....:.|.:|:
Mosquito   696 KVVTVIA--PLAELGDYSTVLRTISSGTASVSMEPNGHSPLNESDEAQAMRR 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	218/744 (29%)
mRRF2	XP_061516391.1	None