Protein Alignment CG13784 and SLC66A2

DIOPT Version :10

• Sequence 1: NP_001260176.1
• Gene: CG13784 / 34003
• FlyBaseID: FBgn0031897
• Length: 969
• Species: Drosophila melanogaster
• Sequence 2: XP_047293784.1
• Gene: SLC66A2 / 80148
• HGNCID: 26188
• Length: 296
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 128/305 - (41%)
• Similarity: 169/305 - (55%)
• Gaps: 56/305 - (18%)

  Fly     1 MDWIINDEMGLTVGHVVGWAAASAMVIGGVIPYVPQYIEIKKTQDAEGFSLYVCLALLVANSLRI 65
            :||::     :.:..:|.|.||:|||.|||:||||||.:|::||:|:|||.||||.|||||.|||
Human     6 LDWLL-----VPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVANILRI 65

  Fly    66 LFW-------------------------FSSRYELPLLVQSVVMNVTMFLMIHLCVKVK---RVN 102
            ||.                         |..|:|.|||.||.:|.:||.||:.||.:|:   .:|
Human    66 LFCPYYHFAKPAFSRSHSVECQHSGFGRFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELN 130

  Fly   103 ANNREHALRGDELHLPKVMTDTDTGASISTEAGGSVLKRVRSRHYLNDLDFKYFWNWTDFQSYLD 167
            |..|..                 |.|....|.     .:|..|....|.|..:||.|:.|..|:.
Human   131 ARRRSF-----------------TAADSKDEE-----VKVAPRRSFLDFDPHHFWQWSSFSDYVQ 173

  Fly   168 FMLVVWAVGAAITYLMLSVLWFMESMGFVAVFTEAMLGAPQFLRNFKNKSTYGMSIHMVIMWTLG 232
            .:|....|...||||.:....|:|::||:||.||||||.||..||.:::||.||||.||:|||.|
Human   174 CVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSG 238

  Fly   233 DMFKTGYFIVRKAPSQFWICGTLQVSLDIAILSQVW-FYRKNSKP 276
            |.|||.||:::.||.||.:||.|||.:|:|||.|.: |.|...||
Human   239 DAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYAFARHPQKP 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13784	NP_001260176.1	PQ-loop	17..77	CDD:461220	40/84 (48%)
		PQ-loop	189..249	CDD:461220	36/59 (61%)
SLC66A2	XP_047293784.1	PQ-loop	17..68	CDD:461220	36/50 (72%)
		PQ-loop	195..255	CDD:461220	36/59 (61%)