DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13784 and pqlc1

DIOPT Version :9

Sequence 1:	NP_001260176.1	Gene:	CG13784 / 34003	FlyBaseID:	FBgn0031897	Length:	969	Species:	Drosophila melanogaster
Sequence 2:	XP_021323964.1	Gene:	pqlc1 / 101883969	-ID:	-	Length:	270	Species:	Danio rerio

Alignment Length:	312	Identity:	136/312 - (43%)
Similarity:	185/312 - (59%)	Gaps:	50/312 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDWIINDEMGLTVGHVVGWAAASAMVIGGVIPYVPQYIEIKKTQDAEGFSLYVCLALLVANSLRI 65
            ||.:|.|::...|..||.|.|:.|::.||::||:|||.:|::||:|||||.||||.|||||.|||
Zfish     1 MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRI 65

  Fly    66 LFWFSSRYELPLLVQSVVMNVTMFLMIHLCVKVK---RVNANNREHAL---RGDELHLPKVMTDT 124
            ||.|...:|.|||.||::|.|||.:|::||..|:   .:|...|....   :.:|:.:||
Zfish    66 LFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTATDSKDEEIKVPK----- 125

  Fly   125 DTGASISTEAGGSVLKRVRSRHYLNDLDFKYFWNWTDFQSYLDFMLVVWAVGAAITYLMLSVLWF 189
                                |.:| |.|:.|||:|:.|..||..:|....:.|.:|||:|..:.|
Zfish   126 --------------------RLFL-DFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLF 169

  Fly   190 MESMGFVAVFTEAMLGAPQFLRNFKNKSTYGMSIHMVIMWTLGDMFKTGYFIVRKAPSQFWICGT 254
            :||:||:|||||||||.||...|::||||.||||.||:|||.||.||||||::.:||.||||||.
Zfish   170 VESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGL 234

  Fly   255 LQVSLDIAILSQVWFYRKNSKPRDLRRGDXQFAPEEQPQHIHHHDIHTSHSE 306
            |||.:|..||.||::|                  ...||....|..||:.::
Zfish   235 LQVCVDFTILFQVYYY------------------SHYPQKPISHTTHTTSAK 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13784	NP_001260176.1	PQ-loop	18..76	CDD:282099	34/57 (60%)
CG13784	NP_001260176.1	PQ-loop	193..248	CDD:282099	37/54 (69%)
pqlc1	XP_021323964.1	PQ-loop	18..74	CDD:309357	33/55 (60%)
pqlc1	XP_021323964.1	PQ-loop	173..226	CDD:309357	35/52 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583530
Domainoid	1	1.000	57	1.000	Domainoid score	I10854
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004636
OrthoInspector	1	1.000	-	-		otm25817
orthoMCL	1	0.900	-	-		OOG6_103454
Panther	1	1.100	-	-	LDO	PTHR14856
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.840