DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4502 and Ube2ql1

DIOPT Version :9

Sequence 1:	NP_609103.1	Gene:	CG4502 / 34002	FlyBaseID:	FBgn0031896	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001138634.1	Gene:	Ube2ql1 / 76980	MGIID:	1924230	Length:	304	Species:	Mus musculus

Alignment Length:	322	Identity:	139/322 - (43%)
Similarity:	187/322 - (58%)	Gaps:	42/322 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VVTAFRKIFHKSSNNNNNNNNNHNNNINNNNNNDKVDGATGSSPNINNNNNNNNNNNNHDGAAAP 73
            :.|..|||.....:|.:..:..|::|........:.....|.... .::.:.......|.|.:..
Mouse     1 MATLLRKIGLIRLHNRDTEDPKHHHNHRGGGGGQQSASLRGKGGG-KSSGHKQQQQQQHPGGSGD 64

  Fly    74 SSAG---GVA--------------VAGGAVGSSGSSGAAKNAVVRMA------AEQAVWDSPGKR 115
            :|.|   |.:              .|.||.|::|:.|..:.|....|      |..|...|....
Mouse    65 ASPGPGKGKSKRAAELAARDKQPQPAAGAAGAAGAGGPRERAAGARAGPGPAVAAAAAGGSLVPA 129

  Fly   116 RRQDHKVAPTTERQLVAAPDHTIRTRRLMKEYREMERLQAKNDAVFTVELVNDSLFEWHVRLHVI 180
            .||.|    .|:          :|:||||||.:::.||   :|...:|||||::||:|:|:||.:
Mouse   130 ARQQH----CTQ----------VRSRRLMKELQDIARL---SDRFISVELVNENLFDWNVKLHQV 177

  Fly   181 DPDSPLARDMAEMGVPAILLHLSFPDNFPFAPPFMRVVEPHIEKGYVMEGGAICMELLTPRGWAS 245
            |.||.|.:||.|.....|||:|:|||||||:||||||:.|.:|.|||::||||||||||||||:|
Mouse   178 DKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSS 242

  Fly   246 AYTVEAVIMQFAASVVKGQGRIARKP-KSTKEFTRRQAEESFRSLVKTHEKYGWVTPALSDG 306
            |||||||:.|||||:|||||||.||. ||.|.|:|::||.:|:||||||||||||||.:|||
Mouse   243 AYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4502	NP_609103.1	UBCc	140..>258	CDD:238117	73/117 (62%)
Ube2ql1	NP_001138634.1	UBCc	140..>258	CDD:238117	76/120 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849704
Domainoid	1	1.000	151	1.000	Domainoid score	I4350
eggNOG	1	0.900	-	-		E1_KOG0897
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15975
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3531
Isobase	1	0.950	-	0	Normalized mean entropy	S1825
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214134at2759
OrthoFinder	1	1.000	-	-		FOG0008145
OrthoInspector	1	1.000	-	-		oto92330
orthoMCL	1	0.900	-	-		OOG6_109648
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4130
SonicParanoid	1	1.000	-	-		X6105
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740