DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4496 and CG8478

DIOPT Version :9

Sequence 1:	NP_001285707.1	Gene:	CG4496 / 34000	FlyBaseID:	FBgn0031894	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_001163576.1	Gene:	CG8478 / 41194	FlyBaseID:	FBgn0037746	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	83/411 - (20%)
Similarity:	145/411 - (35%)	Gaps:	129/411 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 QEVIELDEEEAQ---SPRGLIISAARSLAHWNSSIRRVTPDIELIPRRVHRVVAEIELSDSDHDE 169
            :.:.|:..|...   ||.|    |.:.:||.|..:..|:   |||.:.: ::.|     ||....
  Fly   207 ENITEVSNEGVSMLVSPAG----AEKEVAHVNEVVNEVS---ELIAKAL-KISA-----DSVKPA 258

  Fly   170 DSEVDEDVSLPSNAVSCVLNEQRQDGSQNPQELVIIVPSDQED------EQKTDNVIKRKSSGSR 228
            .|::..:......::|...:     |:..|:.....:|:...:      :|:...|:|...:...
  Fly   259 TSKLKVEAGKKRQSMSSTYS-----GAALPRPRRSYLPTTTAETRTYSFKQRMSVVVKTTLNSPA 318

  Fly   229 RLVKRRPGA----NRRGRHMYECPDCGKKVQSNYNLRRHMMIHT-------------------GE 270
            |  ||..|.    :||     .|....|..:|  ::|:.:.:.:                   .|
  Fly   319 R--KRSVGGGVSLSRR-----SCLPVSKLTKS--SIRKSLAVTSVRSPEKIASKPAKTSTKSIPE 374

  Fly   271 RPFPCDLCERRFREFSDLKKHRRRHSHDPQFICMICHLGA---------PLEQ--DSTRCADCES 324
            :.|.|..|...||..|.|..|.|  .|||      ...||         |:..  ...||..|:
  Fly   375 KVFSCKNCSTTFRVKSLLDVHMR--MHDP------VDNGANTLKRLNSNPVAAGVSKNRCKFCD- 430

  Fly   325 KNLMVKPQPEELGEKTTEEH----SDEM-EGDDDEIEEAALENEKQPQ---------------VA 369
            ||..:        |:....|    .|:: ..:..::|...|.:||:.|               :.
  Fly   431 KNFAL--------ERALHIHLMQNCDKIPPSEKRKLEFTELNHEKKAQLPKIGGTSGINHPMTMP 487

  Fly   370 TQPSLMVTLIPPIQSPPEKVPSHTQPSRPPLPRSCSSANSSSSLSNDGNIAGKSMSRT-RRSYPC 433
            .:|...::.||.: :|.:...|...||...:|:               |:|...:.|| .::.||
  Fly   488 QKPQQRISTIPKL-APSQGTQSMAPPSVKKIPK---------------NVAHAGVYRTPTKTVPC 536

  Fly   434 PLCHRPFG-----TRHNLKRH 449
            .:|.:.|.     |.|:|..|
  Fly   537 HICKQSFRSILEFTNHSLTVH 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4496	NP_001285707.1	zf-C2H2	245..267	CDD:278523	4/21 (19%)
		C2H2 Zn finger	247..267	CDD:275368	4/19 (21%)
		zf-H2C2_2	259..282	CDD:290200	5/41 (12%)
		C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		zf-C2H2	431..453	CDD:278523	8/24 (33%)
		C2H2 Zn finger	433..453	CDD:275368	7/22 (32%)
		zf-H2C2_2	445..468	CDD:290200	2/5 (40%)
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	489..510	CDD:275368
CG8478	NP_001163576.1	zf-C2H2	377..399	CDD:278523	9/23 (39%)
		C2H2 Zn finger	379..399	CDD:275368	8/21 (38%)
		C2H2 Zn finger	426..444	CDD:275368	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100