DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4496 and CG9609

DIOPT Version :9

Sequence 1:	NP_001285707.1	Gene:	CG4496 / 34000	FlyBaseID:	FBgn0031894	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	78/355 - (21%)
Similarity:	116/355 - (32%)	Gaps:	129/355 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 KRRPG-ANRRGRHMYEC--PDCGKKVQSNYNLRRHMMIHTGERPFPCDL--CERRFREFSDLKKH 291
            |:|.| .|..|...|.|  |.|....:....|.||...|||.:...|..  |::.:...:.||:|
  Fly    21 KQRQGRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYSIVTHLKRH 85

  Fly   292 RRRHSHDPQFICMICHLGAPLEQDSTRCADCESKNLMVKPQPEELGEKTTEEHSDEMEGDDDEIE 356
             .|.:|:                                 :||...:||.
  Fly    86 -LRSTHE---------------------------------RPESAAKKTV--------------- 101

  Fly   357 EAALENEKQPQVATQPSLMVTLIPPIQSPPEKVPSHTQPSRPPLPRSCSSANSSSSLSNDGNIAG 421
            :.|||                                         .||  ....|:||    ..
  Fly   102 KCALE-----------------------------------------ECS--KMFISVSN----MT 119

  Fly   422 KSMSRTRRS---YPCPLCHRPFGTRHNLKRHYM-IHTGEKPFSCSKCRKPFRECSTLKKHMVTHV 482
            :.|..|..|   |||..|...|..:..||||.: .||.|.|:|||||.:.|.:....:.|   ..
  Fly   120 RHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSH---EP 181

  Fly   483 RDRWYKCLRCPSKFRDYLEYSDH-------KNNHQDQLSSRKSSIYESDDDGDSSVE----DCLE 536
            ..:.|:|..||.:|..:..|:.|       ||.|:   ..|..|.::...:....:|    :..:
  Fly   182 SCKLYECPGCPLQFDKWTLYTKHCRDSLHGKNRHK---CDRCDSAFDKPSELKRHLEVKHKEAAQ 243

  Fly   537 CCECQQRFT-------ELDAYTAHLKKHDL 559
            ..||...||       :..:|..:|::|.|
  Fly   244 TDECATSFTCNEEGCGKSYSYLRNLRQHML 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4496	NP_001285707.1	zf-C2H2	245..267	CDD:278523	7/23 (30%)
		C2H2 Zn finger	247..267	CDD:275368	6/21 (29%)
		zf-H2C2_2	259..282	CDD:290200	8/24 (33%)
		C2H2 Zn finger	275..295	CDD:275368	5/21 (24%)
		zf-C2H2	431..453	CDD:278523	9/22 (41%)
		C2H2 Zn finger	433..453	CDD:275368	7/20 (35%)
		zf-H2C2_2	445..468	CDD:290200	13/23 (57%)
		C2H2 Zn finger	461..481	CDD:275368	6/19 (32%)
		C2H2 Zn finger	489..510	CDD:275368	8/27 (30%)
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	5/18 (28%)
		zf-C2H2_8	67..150	CDD:292531	29/178 (16%)
		C2H2 Zn finger	67..90	CDD:275368	6/23 (26%)
		C2H2 Zn finger	106..126	CDD:275368	7/66 (11%)
		C2H2 Zn finger	134..155	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..210	CDD:275368	6/21 (29%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		C2H2 Zn finger	253..276	CDD:275368	4/21 (19%)
		C2H2 Zn finger	283..302	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100