Protein Alignment ACADM and Acox3

DIOPT Version :10

• Sequence 1: NP_001272972.1
• Gene: ACADM / 34
• HGNCID: 89
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_001137800.1
• Gene: Acox3 / 33898
• FlyBaseID: FBgn0031813
• Length: 724
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 108/491 - (21%)
• Similarity: 173/491 - (35%)
• Gaps: 167/491 - (34%)

Human    18 FHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAW 82
            :.|..||  .:.|||||...     |:.:|.   |.|  |:.::                    |
  Fly    85 WQWMEQH--PDYQREPGSDL-----ERTREM---ANK--RQHLL--------------------W 117

Human    83 ELGLMNTHIPENCDYSVCPLLEACTLYLDAFFLLLTGSNLNLHLNLGGLGLGTFDACLISEELAY 147
            |...          |.|       ..||....|||                 .|...:.|.:.:
  Fly   118 EQQF----------YGV-------NEYLGTPHLLL-----------------AFGQAIFSYDFS- 147

Human   148 GCTGVQTAIE-GNSLGQMPIIIAGNDQQK-KKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA- 209
                  |::: |.|.|..|..:..|...: .||:.::.:..::.||.:||...|::..|::|:|
  Fly   148 ------TSVKFGLSTGMFPSTLVSNGSGRLGKYVAKIADNRILGAYALTEISHGTNALGMRTRAT 206

Human   210 -EKKGDEYIIN-----GQKMWITNGGK--------ANWYFLLARSDPDPKAPANKAFTGFIVEAD 260
             :.|..|:||:     ..|.|:.|.||        |..|.      ||.|....:||...|.:..
  Fly   207 YDVKRQEFIIHTPDFEAAKCWVGNLGKTCTHAIVYAQLYV------PDDKHQGLQAFLVPIRDER 265

Human   261 T----PGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVL--IGD------------------GA 301
            |    ||:.:|.....:|....|...::|...::||.|:|  .||                  ||
  Fly   266 TLLPFPGVTVGDMGEKIGLNGIDNGFVMFNQYRIPKANLLSKTGDIDAQGNYTSKIKDERKRLGA 330

Human   302 GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKL-------LVEHQAISF-MLAE 358
                ::||....|..:.|.......:|:..||:||..|:.||..       ::|:|:..: ::..
  Fly   331 ----SLGALSVGRVNITAITYVALSKAVTIATRYAASRRQFGPTNSPAEWPVIEYQSQQYRLIPH 391

Human   359 MAMKVELARMSYQRAA--WEVDSGRRNTYYASIAKAFAGD------------------IANQLAT 403
            :|..:.|      |.|  |   .|:.|....  .|.|.|:                  :|...|.
  Fly   392 LATTIAL------RVATLW---IGKENVDLT--MKGFTGEDTSQAGMEIHAISSALKPVATWAAR 445

Human   404 DAVQ----ILGGNGFNTEYPVEKLMRDAKIYQIYEG 435
            |.:|    ..||:|:.....:.:|..|......|||
  Fly   446 DGIQECREACGGHGYLKSSGLGELRNDNDANCTYEG 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACADM	NP_001272972.1	MCAD	41..451	CDD:173846	100/468 (21%)
Acox3	NP_001137800.1	ACAD	52..694	CDD:447864	108/491 (22%)