Protein Alignment MICU1 and Micu2

DIOPT Version :9

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_082919.1
• Gene: Micu2 / 68514
• MGIID: 1915764
• Length: 432
• Species: Mus musculus
• Alignment Length: 412
• Identity: 112/412 - (27%)
• Similarity: 192/412 - (46%)
• Gaps: 77/412 - (18%)

  Fly   140 AGSDLHLHEGKKIREKVGFRE--RKIIEYEN---RIRQFSTPDKVFRYFATIQVPVADDRH--EV 197
            ||:....|.|   |.|...||  |.:...:|   .|.:.|...:.|..|::::       |  |.
Mouse    45 AGAGAAWHHG---RVKAAAREGSRTVSAQKNYLGPIEKLSLRKQRFMQFSSLE-------HDGEY 99

  Fly   198 YMTPTDFLTSMTPGMKQPDGLGLDQYRRYDPKSVGEQL-NLHLEK-----------NSIFYKLGS 250
            ||||.|||.|:             .:.:.:.|::.::| ...:|.           ::.|..||.
Mouse   100 YMTPRDFLFSV-------------MFEQVERKTLVKKLAKKDIEDVLSGIQTARCGSTFFRDLGD 151

  Fly   251 YGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGDVDCEEFEMVATLVRQQ---TSMGTRHRD 312
            .|:|::::|:||||:|:.....|.:||:|.|::|:..::.:||..:..::.:|   .::.|...:
Mouse   152 KGVISYTEYLFLLTILTKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTVKTNETE 216

  Fly   313 HANTGNTFKGVNSALITYFFGPNMDEKLTIEKFLDFQEQLQREILSLE---------FERKEPND 368
            :.:......|||:.|...|||...::||..::|..|.|.||.|:..:|         |.|||
Mouse   217 YQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKE--- 278

  Fly   369 EGNITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGKGISKQDYLDFFHFLNNINDVDTALT 433
                   ||||.||.:..  .:.|....:.|:.:. ..|:.||..::..|.||..::.|...|:.
Mouse   279 -------DFAEWLLFFTN--TENKDIYWRNVREKL-SVGESISLDEFKSFCHFTTHLEDFAIAMQ 333

  Fly   434 FYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQLSNKEFISVMKNRVQRGLEK 498
            .:.:|...:.....:...|......|||:::|.||.|||.:.|..||:.||:.|:|||:.|||
Mouse   334 MFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRGL-- 396

  Fly   499 PKDTGFLKMMRSV---FKCAKE 517
                 ::...:||   :||.|:
Mouse   397 -----WVSQQQSVQEYWKCVKK 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh	<252..293	CDD:298682	14/40 (35%)
		EF-hand_8	438..491	CDD:290545	18/52 (35%)
Micu2	NP_082919.1	EF-hand_8	345..391	CDD:290545	17/45 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54184
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830