Protein Alignment MICU1 and micu3a

DIOPT Version :9

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_021326830.1
• Gene: micu3a / 559552
• ZFINID: ZDB-GENE-070713-1
• Length: 544
• Species: Danio rerio
• Alignment Length: 425
• Identity: 111/425 - (26%)
• Similarity: 187/425 - (44%)
• Gaps: 99/425 - (23%)

  Fly   163 IIEYENRIRQFSTPDKVFRYFATIQVPVADDRHEVYMTPTDFLTSMT---PGMKQPDGLGLDQYR 224
            :.:::......|:.:..||.|::::.     ..::||||.:|:.|:|   |.:|:|
Zfish   138 VFDFDETDVYMSSHEHRFRLFSSVEY-----EGQLYMTPQNFIESVTMSEPRIKKP--------- 188

  Fly   225 RYDPKSVGEQLNLHLEK------------NSIFYKLGSYGLITFSDYIFLLTVLSISRRHFEIAF 277
               .:|:.:|   .|||            :.:|..|...|:|.:::|:|||.:|:.....|:|||
Zfish   189 ---WRSLTKQ---ELEKILSDTPPVWKGTSKLFRNLRERGIIAYTEYLFLLCILTKPHAGFKIAF 247

  Fly   278 RMFDLNGDGDVDCEEFEMVATLVRQQTSMGTRHRD------------------------------ 312
            .|||.:|:..||..||.::..:.|::.....|..|
Zfish   248 NMFDADGNQMVDKREFMVLQEIFRKKNEKKGRKGDAEKSAQLSMQLYGYQVAPVNSVLKKESQEF 312

  Fly   313 -----------------HANTGNTFK--------GVNSALITYFFGPNMDEKLTIEKFLDFQEQL 352
                             .::....||        .:::.|:.:|||.....:||.:.|..|.:.|
Zfish   313 VPRSYWDKLRRGASQALFSDLAEDFKLERADENMMIDTTLLVHFFGKKGKAELTFDDFYRFMDNL 377

  Fly   353 QREILSLEFERKEPNDEG--NITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGK--GISKQ 413
            |.|:|.:||   ....:|  .|:|.|||.:||.|..  ::..:..|:.|::...|..|  ||:.:
Zfish   378 QTEMLEIEF---LTYSKGMTTISEEDFARILLRYTN--VEDIRSYLENVRQCIPDEKKPEGITFE 437

  Fly   414 DYLDFFHFLNNINDVDTALTFYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQ 478
            ::..||.||||:.|...|:..|:.|..||.|............:.|:.|:|:.:|.|||.::|:|
Zfish   438 EFRSFFQFLNNLEDFAIAMQMYNFACRSIGQDEFARAVYVATGLKLTRHLVNTIFKIFDVDHDDQ 502

  Fly   479 LSNKEFISVMKNRVQRGLEKPKDTGFLKMMRSVFK 513
            ||.||||.:||:|:.||....|........||..|
Zfish   503 LSYKEFIGIMKDRLHRGGRGYKSVERFTSFRSCLK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh	<252..293	CDD:298682	17/40 (43%)
		EF-hand_8	438..491	CDD:290545	21/52 (40%)
micu3a	XP_021326830.1	HAD_like	138..>223	CDD:328728	21/104 (20%)
		EFh_MICU3	242..516	CDD:320083	76/278 (27%)
		EF-hand motif	242..271	CDD:320083	12/28 (43%)
		EF-hand motif	351..381	CDD:320083	10/29 (34%)
		EF-hand motif	450..479	CDD:320083	7/28 (25%)
		EF-hand motif	487..516	CDD:320083	15/28 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820