Protein Alignment MICU1 and micu2

DIOPT Version :9

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001017539.2
• Gene: micu2 / 548335
• ZFINID: ZDB-GENE-030131-3374
• Length: 419
• Species: Danio rerio
• Alignment Length: 375
• Identity: 107/375 - (28%)
• Similarity: 178/375 - (47%)
• Gaps: 72/375 - (19%)

  Fly   170 IRQFSTPDKVFRYFATIQVPVADDRHEVYMTPTDFLTSMTPGMKQPD---------GLGLDQYRR 225
            :.|.|...:.|..||::   :.:|  |.||||.|||.|:.  |::.|         ...||:..:
Zfish    71 VPQMSMRRRRFNQFASM---IYED--EPYMTPRDFLHSVL--MEKVDHKLKKKVLTKADLDEMIK 128

  Fly   226 YDPKSVGEQLNLHLEKNSIFYKLGSYGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGDVDC 290
            ...|:..        .|::|..:|..|||::::|:||||:::.|...|.|||:|.|::|...||.
Zfish   129 VASKAEA--------GNNLFRGIGDKGLISYTEYLFLLTIITKSDTGFHIAFKMLDIDGSETVDK 185

  Fly   291 EEFEMV-------ATLVRQQTSMGTRHRDHANTGNTFKGVNSALITYFFGPNMDEKLTIEKFLDF 348
            .||:.:       ..|:||.   ||...|:|:.      |::.|..:|||.:.::||..:.|..|
Zfish   186 MEFQKLKKVNGPKKELLRQG---GTELSDNADE------VDTTLQVFFFGKDGNKKLQYKDFCRF 241

  Fly   349 QEQLQREILSLEFERKEPNDEGNITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGKGISKQ 413
            .|.||.|:..:||.:.....: .:...||||.||.:..   ::..:..:...|:....|:.|:..
Zfish   242 MEDLQAEVQEVEFTQFSKGMK-TMRREDFAEWLLHFTN---EEDNEAYQDNMRKRIPTGQSITFD 302

  Fly   414 DYLDFFHFLNNINDVDTALTFYHIAGASIDQQTLQHVAKTVAMV------------NLSDHVVDV 466
            ::.:|            .|..||:...:|..:.....:|.:.:.            .|||:|:|.
Zfish   303 EFKEF------------CLFTYHLEDFAISVKMSIEGSKPIGLAQFKRAVMIATGHELSDNVLDT 355

  Fly   467 VFTIFDENNDNQLSNKEFISVMKNRVQRGLEKPKDTGFLKMMRSVFKCAK 516
            ||.:||.:.|:.||:|||::|||:||.|||......|    :...:||.|
Zfish   356 VFKLFDMDGDDCLSHKEFLAVMKDRVHRGLRVQPQYG----VSGYWKCVK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh	<252..293	CDD:298682	18/40 (45%)
		EF-hand_8	438..491	CDD:290545	20/64 (31%)
micu2	NP_001017539.2	EF-hand_7	171..242	CDD:290234	24/79 (30%)
		EFh	171..242	CDD:298682	24/79 (30%)
		EF-hand_8	331..380	CDD:290545	18/48 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54184
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830