Protein Alignment MICU1 and micu2

DIOPT Version :9

• Sequence 1: NP_001097110.1
• Gene: MICU1 / 33999
• FlyBaseID: FBgn0031893
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_002940795.2
• Gene: micu2 / 100486652
• XenbaseID: XB-GENE-994925
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 414
• Identity: 112/414 - (27%)
• Similarity: 182/414 - (43%)
• Gaps: 94/414 - (22%)

  Fly   130 SESEDSEDEEAGSDLHLHEGKKIREKVGFRERKIIEYENRIRQFSTPDKVFRYFATIQVPVADDR 194
            ::.||:.||       ..|.:.|| |..|.:...::||.
 Frog    66 AQKEDANDE-------AKENQSIR-KQRFMQFASLKYEG-------------------------- 96

  Fly   195 HEVYMTPTDFLTSMTPGMKQPDGLGLDQYRRYDPKSVGEQLN-----------LHLEKNSIFYK- 247
             |.||||.|||.|:             .:.:.:.:::.:.|.           ...:..|:|::
 Frog    97 -EYYMTPRDFLFSV-------------MFEQMERRTISKPLTKKELDAMLSQATKAKPGSMFFRD 147

  Fly   248 LGSYGLITFSDYIFLLTVLSISRRHFEIAFRMFDLNGDGDVDCEEFEMVATLVRQQTSM-----G 307
            ||..|||::::|:||||:|:..:..|.|||.|.|.:|:..|:..||..:..::..:..|     |
 Frog   148 LGDKGLISYTEYLFLLTILTKPQTGFRIAFNMLDTDGNEQVEKREFFKLQRILGHKEDMKMSPGG 212

  Fly   308 TRHRDHANTGNTFKGVNSALITYFFGPNMDEKLTIEKFLDFQEQLQREILSLE---------FER 363
            .......:|.::  .||:.|:.:|||....|||...:|..|.|.||.|:..:|         |.|
 Frog   213 VTSTQEPSTDSS--DVNTTLLVHFFGRGGREKLQYSEFYKFMENLQTEVQEMEFIQFSKGLNFMR 275

  Fly   364 KEPNDEGNITEADFAELLLAYAGYPLKKKQKKLKRVKRRFRDHGKGISKQDYLDFFHFLNNINDV 428
            ||          ||||.||.:...  :......:.|:.|. ..|:.||..::..|:.|:||:.|.
 Frog   276 KE----------DFAEWLLFFTDE--ENNDVYWQNVQARI-PPGESISMDEFKSFYQFMNNLEDF 327

  Fly   429 DTALTFYHIAGASIDQQTLQHVAKTVAMVNLSDHVVDVVFTIFDENNDNQLSNKEFISVMKNRVQ 493
            ...:..:..|..:|.....:...|......||::|:|.||.|||.:.||.||:.||:.|::||:.
 Frog   328 SITMKLFSSANRAIKMAEFKRAVKVATGQELSNNVLDTVFKIFDLDGDNCLSHGEFLGVLRNRLH 392

  Fly   494 RGLEK-PKDTGFLKMMRSVFKCAK 516
            |||:. |:..|    :...:||.|
 Frog   393 RGLKHVPQQQG----VHGYWKCVK 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICU1	NP_001097110.1	EFh	<252..293	CDD:298682	17/40 (43%)
		EF-hand_8	438..491	CDD:290545	19/52 (37%)
micu2	XP_002940795.2	EFh_MICU2	172..391	CDD:320082	69/233 (30%)
		EF-hand motif	172..201	CDD:320082	10/28 (36%)
		EF-hand motif	229..259	CDD:320082	12/29 (41%)
		EF-hand motif	325..354	CDD:320082	4/28 (14%)
		EF-hand motif	362..391	CDD:320082	15/28 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010