DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pvf3 and VEGFC

DIOPT Version :9

Sequence 1:NP_001097107.1 Gene:Pvf3 / 33995 FlyBaseID:FBgn0085407 Length:651 Species:Drosophila melanogaster
Sequence 2:NP_005420.1 Gene:VEGFC / 7424 HGNCID:12682 Length:419 Species:Homo sapiens


Alignment Length:232 Identity:55/232 - (23%)
Similarity:95/232 - (40%) Gaps:66/232 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   442 HAQKQ-----KSERAL--AHAHMN-QVLK-------EATCRIPQKRCQLVQQD----PSKIYTPH 487
            |.::|     ::|..:  |.||.| ::||       :..| :|::.|..|.::    .:..:.|.
Human    92 HNREQANLNSRTEETIKFAAAHYNTEILKSIDNEWRKTQC-MPREVCIDVGKEFGVATNTFFKPP 155

  Fly   488 CTILHRCSEDSGCCPSRSQICAAKSTHNVELHFF---VKSSKHRSVIEKRTFVNHTECHCIER-S 548
            |..::||   .|||.|....|...||..:....|   |..|:....: ..:|.|||.|.|:.: .
Human   156 CVSVYRC---GGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPV-TISFANHTSCRCMSKLD 216

  Fly   549 TYNEETAMAHYGQSVVR----ATILSC-----TCPKSFEKILQDDGQCRC--------------D 590
            .|.:    .|   |::|    ||:..|     |||.::   :.::..|||              |
Human   217 VYRQ----VH---SIIRRSLPATLPQCQAANKTCPTNY---MWNNHICRCLAQEDFMFSSDAGDD 271

  Fly   591 CSSGNYD-CDWLKRGNEHFAMNDRKCIQQGRCKPPTC 626
            .:.|.:| |...|..:|...    :|:.:...:|.:|
Human   272 STDGFHDICGPNKELDEETC----QCVCRAGLRPASC 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pvf3NP_001097107.1 PDGF 464..547 CDD:238079 24/89 (27%)
VEGFCNP_005420.1 PDGF 129..213 CDD:197537 24/88 (27%)
4 X 16 AA repeats of C-X(10)-C-X-C-X(1,3)-C 280..362 6/29 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1364454at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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