DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvf3 and vegfd

DIOPT Version :9

Sequence 1:	NP_001097107.1	Gene:	Pvf3 / 33995	FlyBaseID:	FBgn0085407	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001035268.1	Gene:	vegfd / 678512	ZFINID:	ZDB-GENE-070810-6	Length:	272	Species:	Danio rerio

Alignment Length:	227	Identity:	52/227 - (22%)
Similarity:	82/227 - (36%)	Gaps:	69/227 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 QKQKSERALAHAHMNQVLK------EATCRIPQKRCQLVQQD----PSKIYTPHCTILHRCSEDS 498
            :.::|.|..|.:...::||      :.|..:|::.|..|.::    .:..:.|.|..:.||   .
Zfish    78 ENRRSTRYAAASFSPEMLKDIDDEWQKTQCMPRETCVDVAKELGTNTAVFFKPPCVSVFRC---G 139

  Fly   499 GCCPSRSQIC-------AAKSTHNVELHFFVKSSKHRSVIEKRTFVNHTECHCIERSTYNEETAM 556
            |||......|       ..|:..:|.|..::  |....|:.|  ..|||||.|.|.|........
Zfish   140 GCCNKEGVTCRNTSMTYVNKTILSVSLAPYI--SGPEPVLVK--IANHTECKCQEHSLIRRHARE 200

  Fly   557 AHYGQSVVRATILSCT-CPKSFEKILQDDGQCRCDCSSGNYDCDWLKRGNEHFAMNDRKCI--QQ 618
            .|...        ||: ..|..:|.|         |:.| ...||:.          .:|:  ..
Zfish   201 RHRKN--------SCSPTRKPEDKRL---------CNKG-LIWDWMA----------ERCVTYPS 237

  Fly   619 GRCKPPT------CEFGLYMDKHGRC---PKQ 641
            .:.:||:      ||    ||.. ||   ||:
Zfish   238 SKQEPPSAITEEDCE----MDVE-RCECIPKE 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvf3	NP_001097107.1	PDGF	464..547	CDD:238079	24/93 (26%)
vegfd	NP_001035268.1	PDGF	107..188	CDD:278756	22/87 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1364454at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920