DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvf3 and vegfab

DIOPT Version :9

Sequence 1:	NP_001097107.1	Gene:	Pvf3 / 33995	FlyBaseID:	FBgn0085407	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_001315526.1	Gene:	vegfab / 558154	ZFINID:	ZDB-GENE-030131-4605	Length:	252	Species:	Danio rerio

Alignment Length:	223	Identity:	54/223 - (24%)
Similarity:	83/223 - (37%)	Gaps:	71/223 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   459 QVLKEATCRIPQKRCQLVQQ----DPSKIYTPHCTILHRCSEDSGCCPSRSQICAAKSTHNVELH 519
            :|..::.|| |::....:||    |...|:.|.|.:|.||   :|||......|....|:|:.|.
Zfish    42 EVYNKSLCR-PREMLVEIQQEYPDDTEHIFIPSCVVLTRC---AGCCNDEMMECTPTVTYNITLE 102

  Fly   520 F-FVKSSKHRSVIEKRTFVNHTECHC---------IE-----------RSTYNEE---------- 553
            . .:|..:|:..| ..:|..|:||.|         ||           :...|.|
Zfish   103 IKRLKPLRHQGDI-FMSFAEHSECQCRMKKDLPKEIEKKPRKGKGQKRKGKKNREKKRDLCMAPS 166

  Fly   554 --TAMAH----------YGQSVV----RATILSC-----TCPKSFEKI-LQDDGQCRCDCSSGNY 596
              |:..|          .|::||    .:.|..|     ||.:...:: :||...|:|.|.....
Zfish   167 CLTSAIHTLQPSLWTLRRGKTVVPDQGGSKISQCEPCCSTCSERRRRLFVQDPETCQCSCKHSEA 231

  Fly   597 DCDWLKRGNEHFAMNDRKCIQQGRCKPP 624
            ||     .:....:|:|.|    ||..|
Zfish   232 DC-----RSRQLELNERTC----RCDKP 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvf3	NP_001097107.1	PDGF	464..547	CDD:238079	29/107 (27%)
vegfab	NP_001315526.1	PDGF	49..127	CDD:366040	26/82 (32%)
vegfab	NP_001315526.1	VEGF_C	204..252	CDD:317016	15/56 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1364454at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920