DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvf2 and Vegfa

DIOPT Version :9

Sequence 1:	NP_523499.2	Gene:	Pvf2 / 33994	FlyBaseID:	FBgn0031888	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_114024.2	Gene:	Vegfa / 83785	RGDID:	619991	Length:	393	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	44/217 - (20%)
Similarity:	71/217 - (32%)	Gaps:	64/217 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 EAHRLM----MAKEGICRVPRPEVVHITR----ETNTFYSPRATILHRCSDKVGCCN-AGWTCQM 247
            :||.::    :.:...|| |...:|.|.:    |....:.|....|.||:   |||| ....|..
  Rat   214 KAHEVVKFMDVYQRSYCR-PIETLVDIFQEYPDEIEYIFKPSCVPLMRCA---GCCNDEALECVP 274

  Fly   248 KRNETVDRVFDKVDGRSNEPI-VISMENHTECGCVKVETRRKRSPICLCPKHFKDFSWAGSRAQW 311
            .....|.....::....::.| .:|...|:.|.|...:.|.|.....:..|         .:.|.
  Rat   275 TSESNVTMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGK---------GKGQK 330

  Fly   312 ENEEHLELRLW--------ERRE-------QRCRCDCHLSDETCKRLKNGVEGFSVMERRRIQSG 361
            ...:....:.|        |||:       |.|:|.|..:|..||             .|:::..
  Rat   331 RKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCK-------------ARQLELN 382

  Fly   362 EVSPPFCNYGAYDVRNGRCPRP 383
            |             |..||.:|
  Rat   383 E-------------RTCRCDKP 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvf2	NP_523499.2	PDGF	204..280	CDD:294083	20/81 (25%)
Vegfa	NP_114024.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1364454at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920