DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pvf2 and pdgfbb

DIOPT Version :9

Sequence 1:	NP_523499.2	Gene:	Pvf2 / 33994	FlyBaseID:	FBgn0031888	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_005171668.1	Gene:	pdgfbb / 796490	ZFINID:	ZDB-GENE-131121-332	Length:	483	Species:	Danio rerio

Alignment Length:	206	Identity:	48/206 - (23%)
Similarity:	79/206 - (38%)	Gaps:	65/206 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 IAEQNSVEKLRTMKY----------------NNNRTRELKKRVEAHRLMMAKEGICRVPRPEVVH 213
            :.:..||..::.:::                |::..|..:..::|   ..|::.||:| |.||:.
Zfish    34 LVKAGSVSSIQDLQFLLFSESIEVEPDSHHDNDSSNRLPRSLLDA---QPAQQAICKV-RTEVIE 94

  Fly   214 ITR----ETNTFYS--PRATILHRCSDKVGCCNAGWTCQMKRNETVDRVFD--KVDGRSNEPI-- 268
            :||    .:|..:.  |....:.|||   ||||.. |.|.....|..|...  |:......|:
Zfish    95 VTRSMLDRSNADFLLWPPCVEVQRCS---GCCNTK-TLQCVPVLTHTRYLQVMKIQYVKKRPLYD 155

  Fly   269 --VISMENHTECGC---VKVETRRKRSPICLCPKHFKDFSWAGSRAQWENEEHLELRLWERREQ- 327
              |:|:.:|.||.|   .:...|||.|                       .:.|:.|  :|.|:
Zfish   156 KAVVSVLDHVECRCQPAPRPAHRRKSS-----------------------SQKLDAR--DRSEKS 195

  Fly   328 RCRCDCHLSDE 338
            |.:.|.|..||
Zfish   196 RPKEDLHRRDE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pvf2	NP_523499.2	PDGF	204..280	CDD:294083	27/87 (31%)
pdgfbb	XP_005171668.1	PDGF	86..169	CDD:306779	27/87 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1364454at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920