Protein Alignment Ugt307A1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 131/536 - (24%)
• Similarity: 226/536 - (42%)
• Gaps: 129/536 - (24%)

  Fly    27 PVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLV---TTLPLEEQEIQGNVSHIYIPWQQ 88
            |:|..|.:.:.:            :...|:|:||.:|::   .::.|:.:| ..::..:..|
  Rat    30 PMEYSHWMNIKI------------ILEELVQKGHEVTVLRPSASVFLDPKE-TSDLKFVTFP--- 78

  Fly    89 PKEEVSSSDLILRLERMFRRLEHSGDLLDLPEWKMFLRNQPNTPYDLLLLGY--HFNDHLLGVAA 151
              ...||.|    ||..|.|.        :..|...|.......|.|.|...  .::|:.|.|
  Rat    79 --TSFSSHD----LENFFTRF--------VNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTV-- 127

  Fly   152 HFNCPVAIVSTQ------------------QPTG----------FVNSLMGNPE---ERW----- 180
               |..|:.:.|                  .|.|          |:.||..:|.   |::
  Rat   128 ---CKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEKYIGGVL 189

  Fly   181 ----YVPQPYDGQQRSGISAWVFGMWEKFMEILARRVLARIYRLHFP-------EPQYPSF--ET 232
                |||..:     ||::..:     .|:|    ||...|..|:|.       |.::..|  :|
  Rat   190 FPPSYVPMIF-----SGLAGQM-----TFIE----RVHNMICMLYFDFWFQTFREKKWDPFYSKT 240

  Fly   233 MRRSVVLA---------LSNHHMISEGPIAPLIPSMVDIGGIVLEQQLDKTPLEI-----SAGNR 283
            :.|...||         |...:...|.| .|:.|::..|||:.. :.....|.:|     |:|..
  Rat   241 LGRPTTLAEIMGKAEMWLIRSYWDLEFP-HPISPNVDYIGGLHC-KPAKPLPKDIEDFVQSSGEH 303

  Fly   284 SLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQ 348
            .:::||||:..  |..|:|.......|.||.|. .:.|.:||.....:.   |:.::.||.||..
  Rat   304 GVVVFSLGSMV--RNMTEEKANIIAWALAQIPQ-KVLWRFDGKKPPTLG---PNTRLYKWLPQND 362

  Fly   349 MWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLA 413
            :....|.:.|:||||...:.||:.:|:||:|:||.|:|.||:..|.:|...:.::...::...:.
  Rat   363 LLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVEVNFRTMSKSDML 427

  Fly   414 KAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGAKNLHNPARQLNIIEYHSI 478
            .|:..::::..|.:..:..|.::.|:|..|.|...:|||:::||||||:|.:....|...:|||:
  Rat   428 NALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHSL 492

  Fly   479 DVYFIVYGLLILTIAI 494
            |    |.|.|:..:|:
  Rat   493 D----VIGFLLTCVAV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	110/485 (23%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	131/536 (24%)