Protein Alignment Ugt307A1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 577
• Identity: 138/577 - (23%)
• Similarity: 223/577 - (38%)
• Gaps: 178/577 - (30%)

  Fly    10 LLWMGYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLV--------- 65
            |.|.|  |.|.......|.:..|.|.|            ..:...|..|||.:|::
Mouse    15 LCWAG--CGFCSKVLVWPCDMSHWLNL------------KTILEELGARGHEVTVLKYPSIIIDQ 65

  Fly    66 -TTLPLEEQEIQ---------------GNVSHIYIP----WQQPKEEVSSSDLILRLERMFRRLE 110
             ..:||..:.|.               .|::...||    |:..|          .|:..|  |:
Mouse    66 SKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPNLSLWEAAK----------TLQDFF--LQ 118

  Fly   111 HSGDLLDLPEWKMFLRNQP------NTPYDLLL--------------------------LGYHFN 143
            .:||...:  .:..|.||.      :..||:::                          :||:..
Mouse   119 VTGDFESI--CRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELVAEVLQIPFVYTLRFSMGYYME 181

  Fly   144 DHLLGVAAHFNCPVAIVS------------TQQPTGFVNSLMGNPEERWYVPQPYDGQQRSGISA 196
            .|    ......|::.|.            |::....:.||:   .|.|.  |.||
Mouse   182 KH----CGQLPIPLSYVPVVMSELTDNMTFTERVKNMMFSLL---FEYWL--QQYD--------- 228

  Fly   197 WVFGMWEKF-MEILARRV------------LARIY-RLHFPEPQYPSFETMRRSVVLALSNHHMI 247
              |..|::| .|.|.|..            |.|.| .:.||.|..|:||.
Mouse   229 --FAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEF--------------- 276

  Fly   248 SEGPIAPLIPSMVDIGGIVLE--QQLDKTPLEI--SAGNRSLIIFSLGTRFTWRKSTKELVRTFT 308
                          :||:..:  :.|.|...|.  |:|...:::||||:..  :..|:|......
Mouse   277 --------------VGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSLGSMV--KNLTEEKANLIA 325

  Fly   309 KAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFY 373
            ...||.|. .:.|.|.|...:.:.   .:.::..|.||..:....|.:.||||||...:.||:::
Mouse   326 SVLAQIPQ-KVLWRYSGKKPATLG---SNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYH 386

  Fly   374 GVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRD 438
            ||||:|:|::|||..|:..|::|...|.:|.:.:|...|..|:..::::.||.|..::.|:::.|
Mouse   387 GVPMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHD 451

  Fly   439 RPVSPSDLVTYWIEYIVRHKGAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAIL 495
            :||.|.|...:|||:::||||||:|...|..|:..:|||:|    |.|.|:|.:..|
Mouse   452 QPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLD----VIGFLLLCVVTL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	111/508 (22%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	133/565 (24%)