Protein Alignment Ugt307A1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 141/547 - (25%)
• Similarity: 233/547 - (42%)
• Gaps: 115/547 - (21%)

  Fly     8 WSLLWM--GYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLV---TT 67
            ::|.|.  |...:|       |:|..|.|.:            ..|.|.|..|||...::   .|
  Rat    18 YALPWAEGGKVLVF-------PMEGSHWLSM------------RDVVRELHARGHQAVVLAPEVT 63

  Fly    68 LPLEE-------------------QEIQGNVSHIYIPWQQPKEEVSSSDLILRLERMFRR----L 109
            :.::|                   |::..|:..::......|..:.:|:::..:..:..|    |
  Rat    64 VHIKEEDFFTLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNL 128

  Fly   110 EHSGDL---LDLPEWKMFLRNQPNTPYDLLLLGYHFNDHLLGVAAHFNCPVAIVSTQQPTGFVNS 171
            .|:|.|   |:...:.|.| ..|..|...:|..|      ||:      |........|.|..:.
  Rat   129 LHNGSLLQHLNSSSFDMVL-TDPVIPCGAVLAKY------LGI------PTVFFLRYIPCGIDSE 180

  Fly   172 LMGNPEERWYVPQPYDGQQRSGISAWVFGMWEKFMEILAR-----RVLARIYRLHFPEPQYPSF- 230
            ....|:...|:|.             :..|....|..|.|     ..||..|..||...:|.|.
  Rat   181 ATQCPKPSSYIPN-------------LLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESLA 232

  Fly   231 -ETMRRSVVLALSNHHMISEGPI------------APLIPSMVDIGGI--VLEQQLDKTPLEISA 280
             |.::|.|.|.    .::|...:            .|::|:||.||||  |:::.|.:   |..|
  Rat   233 SELLQREVSLV----EVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKPLSQ---EFEA 290

  Fly   281 -----GNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKV 340
                 |...:::||||:..:.....|.:  ...:|..:.|. .:.|.|.|...|.::   .:..:
  Rat   291 YVNASGEHGIVVFSLGSMVSEIPEKKAM--EIAEALGRIPQ-TVLWRYTGTRPSNLA---KNTIL 349

  Fly   341 AKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTN 405
            .||.||..:....|.|.||||.|...:.|.:..||||:.:||.|||.||.:||:::..|:||:..
  Rat   350 VKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVL 414

  Fly   406 NLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGAKNLHNPARQL 470
            .:|...|..|:..::::.||.|.|::.|.|::|||:.|.||..:|:||::|||||.:|...|..|
  Rat   415 EMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDL 479

  Fly   471 NIIEYHSIDVYFIVYGLLILTIAILRK 497
            ...:|||:||...:..:::..:.|:.|
  Rat   480 TWYQYHSLDVIGFLLAIVLTVVFIVYK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	117/472 (25%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	139/539 (26%)