Protein Alignment Ugt307A1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 557
• Identity: 142/557 - (25%)
• Similarity: 237/557 - (42%)
• Gaps: 115/557 - (20%)

  Fly     6 ISWS---LLWMGY--TCIFLLADSPA------PVESHHILGLFVNVHRSQLMVHLAVCRALLQRG 59
            :.||   ||.:.|  .|:|..:.|.|      |::..|.|.:            |.|.:.|.|:|
Mouse     4 VCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSM------------LGVIQQLQQKG 56

  Fly    60 HHLTLVTTLPLEEQEIQGNVSHIY------IPWQQPKEEVSSS------------DLILRLERMF 106
            |.:.::.    .|..|.......|      :|:|  ||.|:::            ..:||:.:::
Mouse    57 HEVVVIA----PEASIHIKEGSFYTLRKFPVPFQ--KENVTATLVELGRTAFNQDSFLLRVVKIY 115

  Fly   107 RRLEHSGDLL-----DLPEWKMFLRNQPNTPYDLLLLGYHFNDHLLG----VAAHFNCPVAIVST 162
            .:::....:|     .|.....|:.:...:.:|.||     .|..|.    ||.:...|......
Mouse   116 MKVKRDSSMLLAGCSHLLHNAEFMASLEESHFDALL-----TDPFLPCGSIVAQYLTVPTVYFLN 175

  Fly   163 QQPTGFVNSLMGNPEERWYVPQPYDGQ-------QRSGISAWVFGMWEKFM-------------E 207
            :.|....:.....|....|||:.....       ||  :...:..:.|.||             |
Mouse   176 KLPCSLDSEATQCPVPLSYVPKSLSFNSDRMNFLQR--VKNVLLAVSENFMCRVVYSPYGSLATE 238

  Fly   208 ILARRVLARIYRLHFPEPQYPSFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLEQQLD 272
            ||.:.|               :.:.:.....:.|.....:.:.| .|::|:||.||||   ..|.
Mouse   239 ILQKEV---------------TVQDLLSPASIWLMRSDFVKDYP-RPIMPNMVFIGGI---NCLQ 284

  Fly   273 KTPL--EISA-----GNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSA 330
            |.||  |..|     |...:::||||:..:.....|.:  ...:|..:.|. .:.|.|.|...|.
Mouse   285 KKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAM--EIAEALGRIPQ-TVLWRYTGTRPSN 346

  Fly   331 ISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQS 395
            ::   .:..:.||.||..:....|.|.||||.|...:.|.:..||||:.:||.|||.||.:||::
Mouse   347 LA---KNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMET 408

  Fly   396 KNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGA 460
            :..|:||:...:|...|..|:..::::.||.|.|::.|.|::|||:.|.||..:|:||::|||||
Mouse   409 RGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGA 473

  Fly   461 KNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRK 497
            .:|...|..|...:|||:||...:..:::..:.|:.|
Mouse   474 PHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	114/471 (24%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	133/531 (25%)