Protein Alignment Ugt307A1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 519
• Identity: 130/519 - (25%)
• Similarity: 227/519 - (43%)
• Gaps: 98/519 - (18%)

  Fly    36 LFVNVHRSQLMVHLAVCRALLQRGHHLTLV---TTLPLEEQEIQGNVSHIYIPWQQPKEEVSSSD 97
            |.:.:..||.:....|.|.|..|||...::   .|:.::.::.....::.: |:  .|||. ..:
Mouse    31 LVLPMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFTLKTYAF-PY--TKEEY-QQE 91

  Fly    98 LILRLERMFRRLE------------------HSGDLLDLPEWKMFLRNQPNTPYDLLL------- 137
            ::..:|:.|:...                  :|...:.|...||.::...::.:|::|
Mouse    92 ILSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHNKMLIQQLNSSFFDVILTDPIFPC 156

  Fly   138 ---LGYHFNDHLLGVAAHFNCPVAIVSTQQPTGFVNSLMGNPEERWYVPQPYDGQQRSGISAWVF 199
               |..:.....:.:....:|.:...:||.|         ||..  |:|.             :.
Mouse   157 GAVLAKYLQIPAVFILRSLSCGIEYEATQCP---------NPSS--YIPN-------------LL 197

  Fly   200 GMWEKFMEILAR-------RVLARIYRLHFPEPQYPSFETMRRSVVLALSNHHMISEGPI----- 252
            ......|:.|.|       .||..|.||.....:..:.|.::|.|.|.    .::|...:
Mouse   198 TRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLASELLQREVSLV----EVLSHASVWLFRG 258

  Fly   253 -------APLIPSMVDIGGIVLEQQLDKTPL--EISA-----GNRSLIIFSLGTRFTWRKSTKEL 303
                   .|::|:||.||||   ..:.|.||  |..|     |...:::||||:..:.....|.:
Mouse   259 DFVLDYPRPIMPNMVFIGGI---NCVTKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAM 320

  Fly   304 VRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVS 368
              ...:|..:.|. .:.|.|.|...|.::   .:..:.||.||..:....|.|.||||.|...:.
Mouse   321 --EIAEALGRIPQ-TVLWRYTGTRPSNLA---KNTILVKWLPQNDLLGHPKTRAFITHSGSHGIY 379

  Fly   369 EALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKAS 433
            |.:..||||:.:||.|||.||.:||:::..|:||:...:|...|..|:..::::.||.|.|::.|
Mouse   380 EGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLS 444

  Fly   434 QLYRDRPVSPSDLVTYWIEYIVRHKGAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRK 497
            .|::|||:.|.||..:|:||::|||||.:|...|..|...:|||:||...:..:::..:.|:.|
Mouse   445 SLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	112/470 (24%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	130/519 (25%)