Protein Alignment Ugt307A1 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 135/527 - (25%)
• Similarity: 232/527 - (44%)
• Gaps: 109/527 - (20%)

  Fly    27 PVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVT------------------TLPLEEQ 73
            |.:..|.|.:      .:::.||:      :|||.:.::.                  .:|...:
  Rat    32 PQDGSHWLSM------KEIVEHLS------ERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLE 84

  Fly    74 EIQ------GNVSHIYI--PWQQPKEEVSSSDLILRLERMF----RRLEHSGDLLDLPEWKMFLR 126
            |::      || :|...  |...|..|..::.::  ::..|    ..|:.|..|       .|||
  Rat    85 ELRTRYRSFGN-NHFAASSPLMAPLREYRNNMIV--IDMCFFSCQSLLKDSATL-------SFLR 139

  Fly   127 -NQPNTPYDLLLLGYHFNDHLL--GV--AAHFNCPVAIVSTQQPTGFVNSLMGNPEERWYVPQPY 186
             ||    :|.|     |.|..:  ||  |.:...|...:....|....:.|..:|....|||:.|
  Rat   140 ENQ----FDAL-----FTDPAMPCGVILAEYLKLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFY 195

  Fly   187 DG-------QQRSGISAWVFGMWEKFM--------EILARRVLARIYRLHFPEPQYPSFETMRRS 236
            ..       .||  ::.::..:.|.::        ||||..:|.|       :...|:.....
  Rat   196 TKFSDHMTFPQR--LANFIANILENYLYHCLYSKYEILASDLLKR-------DVSLPALHQNS-- 249

  Fly   237 VVLALSNHHMISEGPIAPLIPSMVDIGGI------VLEQQLDKTPLEISAGNRSLIIFSLGTRFT 295
              |.|..:..:.|.| .|::|:|:.|||.      .|.|:.:  ....::|...:::||||:..:
  Rat   250 --LWLLRYDFVFEYP-RPVMPNMIFIGGTNCKKKGNLSQEFE--AYVNASGEHGIVVFSLGSMVS 309

  Fly   296 WRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFIT 360
            .....|.:  ...:|..:.|. .:.|.|.|...|.::   .:..:.||.||..:....|.|.|||
  Rat   310 EIPEKKAM--EIAEALGRIPQ-TVLWRYTGTRPSNLA---KNTILVKWLPQNDLLGHPKARAFIT 368

  Fly   361 HGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSY 425
            |.|...:.|.:..||||:.:||.|||.||.:||:::..|:||:...:|...|..|:..::::.||
  Rat   369 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSY 433

  Fly   426 GETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGAKNLHNPARQLNIIEYHSIDVYFIVYGLLIL 490
            .|.|::.|.|::|||:.|.||..:|:||::|||||.:|...|..|...:|||:||...:..:::.
  Rat   434 KENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLT 498

  Fly   491 TIAILRK 497
            .:.|:.|
  Rat   499 VVFIVYK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	116/473 (25%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	135/527 (26%)