Protein Alignment Ugt307A1 and ugt2a1

DIOPT Version :10

• Sequence 1: NP_609097.2
• Gene: Ugt307A1 / 33993
• FlyBaseID: FBgn0031887
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001177979.1
• Gene: ugt2a1 / 100006320
• ZFINID: ZDB-GENE-080721-20
• Length: 539
• Species: Danio rerio
• Alignment Length: 553
• Identity: 136/553 - (24%)
• Similarity: 223/553 - (40%)
• Gaps: 162/553 - (29%)

  Fly    27 PVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVT--------------------TLPLE 71
            |.|..|.|.:.|            :...|::|||::|:||                    .:|..
Zfish    33 PAEFSHWLNIKV------------ILDVLIERGHNITVVTHTATPSVQTTPSAGYNAEILQVPYT 85

  Fly    72 EQEIQGNVSHIYIPWQQ--PKEEVSSSDLILRLERMF-----------RRLEHSGDLLDLPEWKM 123
            :|||..|:..:...|..  |.:.:.::.  |::..|.           ..|....|||:  :|||
Zfish    86 KQEIVDNLERMLKYWTHDLPNDNIITAS--LKIHEMITTATAQNKITCNALFSRADLLE--KWKM 146

  Fly   124 FLRNQPNTPYDLLL----------------------LGYHFNDHLLGVAAHFNCP------VAIV 160
                   ..:|::|                      |.:.|.:.|..:......|      ||..
Zfish   147 -------EKFDVILADPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPSYVPAVASE 204

  Fly   161 STQQPTGFVNSL-----MGNPEERWYVPQPYDGQQRSGISAWVFGMWEK-FMEILARRV------ 213
            .|.| ..|::.|     .|..:..:|:...:              .|:. :.|:|.:..
Zfish   205 KTDQ-MDFIDRLKNFLFYGMQDFLFYLVTKF--------------KWDHYYSEVLGKPTTMCETM 254

  Fly   214 ------LARIY-RLHFPEPQYPSFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLE--Q 269
                  |.|.| ...:|.|..|:|:.                             :||:..:  :
Zfish   255 GKADIWLIRTYWDFEYPRPFPPNFKF-----------------------------VGGLHCKPAK 290

  Fly   270 QLDKTPLEI--SAGNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAIS 332
            .|.|...|.  |:|:..:::||||:..  :..|.|...|...|..|.|. .:.|.|.|.....::
Zfish   291 PLSKEMEEFVQSSGDHGVVVFSLGSMI--KNLTSERANTIAAALGQIPQ-KVVWRYSGKTPETLA 352

  Fly   333 LDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKN 397
               |:.|:..|.||..:....|.:.||||||...:.||:::||||:||||..||.|||..|::|.
Zfish   353 ---PNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKG 414

  Fly   398 WGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGAKN 462
            ..:.|..|.|....|..|:..:|::.||.|:|::.|:::.|:|:.|.|...||||:::|:||||:
Zfish   415 AAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKH 479

  Fly   463 LHNPARQLNIIEYHSIDVYFIVYGLLILTIAIL 495
            |...|.:|:..:||.:||     ...:|:||.|
Zfish   480 LRVQAHELSWYQYHCLDV-----AAFLLSIAAL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt307A1	NP_609097.2	GT1_Gtf-like	32..450	CDD:340817	114/501 (23%)
ugt2a1	NP_001177979.1	UDPGT	27..526	CDD:278624	136/553 (25%)