DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Caper and NOP13

DIOPT Version :9

Sequence 1:	NP_609095.1	Gene:	Caper / 33989	FlyBaseID:	FBgn0031883	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_014224.2	Gene:	NOP13 / 855547	SGDID:	S000005119	Length:	403	Species:	Saccharomyces cerevisiae

Alignment Length:	287	Identity:	69/287 - (24%)
Similarity:	117/287 - (40%)	Gaps:	57/287 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 ERKRSHSRSRDRNSRRRGTNSPRRRSPPNGADRTTPTELSPEERDARTVFCIQLSQRVRARDLEE 255
            |:|:|.:..:|........|:      |.|.:.....:...::.:...|:...||......||..
Yeast    85 EKKKSGASEKDAQGEESTINT------PTGDESGEVVKKKKKDENKYGVWIGNLSFDTTKDDLVR 143

  Fly   256 FFSSVGKVRD--------------------VRLITCNKTKRFKGIAYIEFDDPESVALALGLSGQ 300
            ||  :.|.:|                    |.....|..|. ||..|:.|.:.|.:...|.||..
Yeast   144 FF--IAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKN-KGFCYMFFKNVEQMKAVLELSES 205

  Fly   301 RLLGVPIMVQHTQAEKNRLQN---AAPAFQPKSHTGPMRLYVGSLHFNITEDMLRGIFEPFGKID 362
            .|.|..::::.::....|...   .|.:..|.|..    |:||:|.|::|:|:||..|:..|.|.
Yeast   206 HLNGRNMLIKDSENYSGRPDKDDLVAMSKNPPSRI----LFVGNLSFDVTDDLLRKHFQHCGDIV 266

  Fly   363 AIQLIMDTETGRSKGYGFITYHNADDAKKALEQLNGFELAGRLM---------------KVGNVT 412
            .|::....::|:.||:.||.:.|.:.:..||:..:..::|||.:               ||.||:
Yeast   267 KIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVS 331

  Fly   413 ERLDMNTTSLDTDE---MDRTGIDLGA 436
            ..   |::|.|...   .||.|.|.|:
Yeast   332 RN---NSSSFDISNNKGYDRAGQDNGS 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Caper	NP_609095.1	RRM1_RBM39_like	238..310	CDD:240729	22/91 (24%)
		RRM2_RBM23_RBM39	337..409	CDD:240730	25/86 (29%)
		RBM39linker	425..500	CDD:292157	5/15 (33%)
		RRM3_RBM39_like	483..567	CDD:240731
NOP13	NP_014224.2	RRM1_Nop13p_fungi	127..217	CDD:409830	22/92 (24%)
NOP13	NP_014224.2	RRM2_Nop13p_fungi	241..316	CDD:409831	24/74 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910