Protein Alignment Caper and TIAL1

DIOPT Version :10

• Sequence 1: NP_609095.1
• Gene: Caper / 33989
• FlyBaseID: FBgn0031883
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001029097.1
• Gene: TIAL1 / 7073
• HGNCID: 11804
• Length: 392
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 71/346 - (20%)
• Similarity: 140/346 - (40%)
• Gaps: 78/346 - (22%)

  Fly   232 EERDARTVFCIQLSQRVRARDLEEFFSSVGKVRDVRLIT-------CNKTKRFKGI--------A 281
            ::...||::...||:.|....:.:.||.:|..:..::||       .|.:..|..:        .
Human     4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYC 68

  Fly   282 YIEFDDPESVALAL-GLSGQRLLGVPIMVQHTQAEKNRLQNAAPAFQPKSHTGPMRLYVGSLHFN 345
            ::||.:....|.|| .::|:::||..:.|...         ..|:.|.|..:....::||.|...
Human    69 FVEFYEHRDAAAALAAMNGRKILGKEVKVNWA---------TTPSSQKKDTSNHFHVFVGDLSPE 124

  Fly   346 ITEDMLRGIFEPFGKIDAIQLIMDTETGRSKGYGFITYHNADDAKKALEQLNGFELAGRLMKVGN 410
            ||.:.::..|.|||||...:::.|..||:||||||::::|..||:.|:..:.|..|.||.::...
Human   125 ITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 189

  Fly   411 VTERLDMNTTSLDTDEMDRTGIDLGATGRLQLMFKLAEGAGLAVPQAAANALLATAPQPAPLQQQ 475
            .|.:.....::.:.:..             ||.|:              :.:..::|:...:...
Human   190 ATRKPPAPKSTQENNTK-------------QLRFE--------------DVVNQSSPKNCTVYCG 227

  Fly   476 EVAPSIATQCFILSNMFDPRTETNPTWDVEIRDDVLEECAKHGGVLHIHVDTISHTGTVYVKCPS 540
            .:|..:..|  ::...|.|                      .|.::.|.|  ....|..:|:..:
Human   228 GIASGLTDQ--LMRQTFSP----------------------FGQIMEIRV--FPEKGYSFVRFST 266

  Fly   541 TTTAVLAVNALHGRWFAGRVI 561
            ..:|..|:.:::|....|.|:
Human   267 HESAAHAIVSVNGTTIEGHVV 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caper	NP_609095.1	SF-CC1	213..578	CDD:273721	71/346 (21%)
TIAL1	NP_001029097.1	RRM1_TIAR	10..107	CDD:410028	21/105 (20%)
		RRM2_TIAR	113..192	CDD:410029	28/78 (36%)
		RRM3_TIAR	222..294	CDD:241064	14/92 (15%)