Protein Alignment Caper and SRSF7

DIOPT Version :10

• Sequence 1: NP_609095.1
• Gene: Caper / 33989
• FlyBaseID: FBgn0031883
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001026854.1
• Gene: SRSF7 / 6432
• HGNCID: 10789
• Length: 238
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 67/178 - (37%)
• Similarity: 81/178 - (45%)
• Gaps: 25/178 - (14%)

  Fly    69 SRSRSGSRDGKSRRDRGNERSSHRDKDKERDRNRDGGDR-----DRHRREGGDRDRERERERERD 128
            ||.|.....|..||.|.:...:.|..| ..||..:.|::     |.||.....|.|.|.|...|.
Human    75 SRVRVELSTGMPRRSRFDRPPARRPFD-PNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRS 138

  Fly   129 RSRR-SRSRDERGGGGRYGDRDKDRRSRD---RRGGSKSLQVDRSRDKRR-RSRSRDQQRKRLSP 188
            |.|| ||||          .|.:.||||.   ||..|.||:..||...|| ||.|....|...||
Human   139 RGRRYSRSR----------SRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSP 193

  Fly   189 IRERKRSHSRSRDRNSRRRGTN-SPRRRSPPNGADRTTPTELSPEERD 235
            .|.|.||.|.||.|:||.:..: ||:|...|:|:.|.:   .|||..|
Human   194 SRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRS---ASPERMD 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caper	NP_609095.1	SF-CC1	213..578	CDD:273721	8/23 (35%)
SRSF7	NP_001026854.1	RRM_SRSF7	12..88	CDD:410050	4/12 (33%)
		Sufficient for interaction with NXF1	81..98		4/16 (25%)
		zf-CCHC	104..119	CDD:395050	3/14 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..238		51/127 (40%)
		6 X 8 AA repeats of R-R-S-R-S-X-S-X	153..226		33/72 (46%)