Protein Alignment Caper and MSI1

DIOPT Version :10

• Sequence 1: NP_609095.1
• Gene: Caper / 33989
• FlyBaseID: FBgn0031883
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 70/286 - (24%)
• Similarity: 114/286 - (39%)
• Gaps: 53/286 - (18%)

  Fly   222 DRTTPTELSPEE-RDARTVFCIQLSQRVRARDLEEFFSSVGKVRDVRLITCNKTKRFKGIAYIEF 285
            |...|...||:. .|...:|...||.:.....|.|:|...|:|::..::....|||.:|..::.|
Human     4 DAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF 68

  Fly   286 DDPESVALALGLSGQRLLGVPIMVQHTQAEKNRLQNAAPAF----QPKSHTGPMRLYVGSLHFNI 346
            .|...|...|..|...|             .::..:...||    |||..|...:::||.|..|.
Human    69 MDQAGVDKVLAQSRHEL-------------DSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNT 120

  Fly   347 TEDMLRGIFEPFGKIDAIQLIMDTETGRSKGYGFITYHNADDAKKALEQLNGFELAGRLMKVGNV 411
            |.:.::..||.|||:|...|:.|..|.|.:|:||:|:.:.|..:|..| ::..|:..::::....
Human   121 TVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE-IHFHEINNKMVECKKA 184

  Fly   412 TERLDMNTTSLDTDEMDRTGIDLGATGRLQLM------FKLAEG----AGLAVPQAAANALLATA 466
            ..:          :.|..||   .|.||.::|      |.|..|    .|......|:.:....|
Human   185 QPK----------EVMSPTG---SARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLA 236

  Fly   467 P-----------QPAPLQQQEVAPSI 481
            |           :..||....|.|.:
Human   237 PGYTYQFPEFRVERTPLPSAPVLPEL 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caper	NP_609095.1	SF-CC1	213..578	CDD:273721	70/286 (24%)
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	18/87 (21%)
		PABP-1234	<32..339	CDD:130689	62/258 (24%)
		RRM2_MSI	110..183	CDD:240769	23/73 (32%)