DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Caper and lem-2

DIOPT Version :9

Sequence 1:	NP_609095.1	Gene:	Caper / 33989	FlyBaseID:	FBgn0031883	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_496944.1	Gene:	lem-2 / 175058	WormBaseID:	WBGene00002275	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	39/204 - (19%)
Similarity:	58/204 - (28%)	Gaps:	66/204 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PRNGSGGGSSHKKQSKRSRSRSGSRDGKSRRDRGNERSSHRDKDKERDRNRDGGDRDRHRREGGD 116
            |::.....|.....::||..|:.:....|..:....||...:.....|..||..|.|.....
Worm    63 PKSAPAPKSPKSPPARRSIPRAAATAANSTINSTFNRSEIEEMSDSDDDMRDDDDDDEEILS--- 124

  Fly   117 RDRERERERERDRSRRSRSRDERGGGGRYGDRDKDRRSRDRRGGSKSLQVDRSRDKRRRSRSRDQ 181
                                            .|.::|..|...|.:..|.|.|.      ....
Worm   125 --------------------------------PKSKQSSFRSANSTASSVGRGRP------VSST 151

  Fly   182 QRKRLSPIRE----------RKRSHSRSRDRNSRRRGTNSPRR-RSPPN------------GADR 223
            ..|||||:.:          ...|.|::....:..|..::||| .|.|.            |:||
Worm   152 PNKRLSPVYKPSPVPKNTPRTTSSSSKTTINTTTTRIPSTPRRITSVPGLITDFTPSFSTFGSDR 216

  Fly   224 --TTPTELS 230
              .||...|
Worm   217 PGATPPRKS 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Caper	NP_609095.1	RRM1_RBM39_like	238..310	CDD:240729
		RRM2_RBM23_RBM39	337..409	CDD:240730
		RBM39linker	425..500	CDD:292157
		RRM3_RBM39_like	483..567	CDD:240731
lem-2	NP_496944.1	LEM_LAP2_LEMD1	3..>35	CDD:240587
lem-2	NP_496944.1	MSC	<384..492	CDD:286487
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900