Protein Alignment Rab30 and RAB9A

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 67/208 - (32%)
• Similarity: 109/208 - (52%)
• Gaps: 18/208 - (8%)

  Fly     7 LFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQERFRS 71
            |||::|:|:.||||:.|:.|:....|......||||:|:.|.:||:|..:.:|||||||||||||
Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71

  Fly    72 ITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLK----ILVGNKTDRDDREIPTQ 132
            :...:||.:...:|.:.:....:|..|.:|.:|...||:.|..:    :::|||.|..:|::.|:
Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTE 136

  Fly   133 IGEEFAKQHDMY-FLETSAKEAENVERLFYEIAAELIGQARSKDGSSSAAAAAAQRQSEGSSIGL 196
            ..:.:.:.:..| :.|||||:|.||...|.|....::......|...........|:.:.|
Human   137 EAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVNLHRKPKPS---- 197

  Fly   197 GSFSAKAAQSNCC 209
                     |:||
Human   198 ---------SSCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	61/165 (37%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	61/164 (37%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		8/13 (62%)