Protein Alignment Rab30 and RAB2B

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 93/226 - (41%)
• Similarity: 137/226 - (60%)
• Gaps: 32/226 - (14%)

  Fly     4 YKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQER 68
            |.:|||.:::|:.||||:||:.:||...|.|....||||:|..:.|.::|::||||||||||||.
Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67

  Fly    69 FRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTDRDD-REIPTQ 132
            |||||:||||.|...:|||||:.:.||:.|..||.:.:::::|.::.:|:|||:|.:. |::..:
Human    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKRE 132

  Fly   133 IGEEFAKQHDMYFLETSAKEAENVERLFYEIAAEL-------------------IGQARSKDGSS 178
            .||.||::|.:.|:|||||.|.|||..|...|.|:                   ||..:|.  |:
Human   133 EGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSI--ST 195

  Fly   179 SAAAAAAQRQSEGSSIGLGSFSAKAAQSNCC 209
            |...:|:||.|.  .||        :.|.||
Human   196 SVGPSASQRNSR--DIG--------SNSGCC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	79/183 (43%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	91/224 (41%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		10/38 (26%)