Protein Alignment Rab30 and RAB7A

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Alignment Length: 172
• Identity: 67/172 - (38%)
• Similarity: 105/172 - (61%)
• Gaps: 7/172 - (4%)

  Fly     5 KFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQERF 69
            |.|.|::::|::|||||.|:.::....|.....||||.||:.|.|.|:...:.:|||||||||||
Human     6 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERF 70

  Fly    70 RSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLK----ILVGNKTDRDDREIP 130
            :|:..::||.|...:||:|::...||..|..|..|....|:.:..:    :::|||.|.::|::.
Human    71 QSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVA 135

  Fly   131 TQIGEE--FAKQHDMYFLETSAKEAENVERLFYEIAAELIGQ 170
            |:..:.  ::|.:..|| |||||||.|||:.|..||...:.|
Human   136 TKRAQAWCYSKNNIPYF-ETSAKEAINVEQAFQTIARNALKQ 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	66/168 (39%)
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	65/169 (38%)
		Switch 1. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	67..82		7/14 (50%)