Protein Alignment Rab30 and rab5d

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_001025576.1
• Gene: rab5d / 594964
• XenbaseID: XB-GENE-489496
• Length: 213
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 134/696 - (19%)
• Similarity: 231/696 - (33%)
• Gaps: 227/696 - (32%)

  Fly    54 PQIVGHYVGVGTVGNLSKDFMNTNNFDPIPGVGEHGDPVVIQ-AKDLLKMQQLFQINRYNLLASD 117
            ||.:...:...:.|.:::.|..:..|.|.....|.....::| .|||||.|... |..|.|..|
 Frog    94 PQCILGRLSEKSSGQMAQKFSFSKVFGPATTQKEFFQGCIMQPVKDLLKGQSRL-IFTYGLTNS- 156

  Fly   118 RIALNRSLPDVRKPKCVSKLYPAK--------LPTTSIIIVFHNEAWSVLLRTVWSVINRSP--- 171
                             .|.|..:        ||.|.      |..:..|...:::.:|..|
 Frog   157 -----------------GKTYTFQGTEENIGILPRTL------NVLFDSLQERLYTKMNLKPHRS 198

  Fly   172 ------------------KGLVREI--LLVDDASDRRFLKHELDNYVQKLPLSVTILRLNKREGL 216
                              ..|:|:|  :.|.:.||        |.....|..|:.|...  .|.:
 Frog   199 REYLRLSSEQEKEEIASKSALLRQIKEVTVHNDSD--------DTLYGSLTNSLNISEF--EESI 253

  Fly   217 VAARLLGARMATGDT----LTFLDAHCECSPGWLEPLLARVQENPKKVVCPVIDIISDD--NFSY 275
            .........||....    ::|.:.:.|.......|:.::.|:  :|::     .:|.|  .:|:
 Frog   254 KDYEQANLNMANSIKFSVWVSFFEIYNEYIYDLFVPVSSKFQK--RKML-----RLSQDVKGYSF 311

  Fly   276 IKSFEFHWGAFNWPLHFRWYTLSDEELAERR-----KDTTTPF----RTPAMAGGLFTIDRKYFF 331
            ||..:             |..:||.:.|.|.     |..:..|    ...:.:..:||:
 Frog   312 IKDLQ-------------WIQVSDSKEAYRLLKLGIKHQSVAFTKLNNASSRSHSIFTV------ 357

  Fly   332 DIGAYDERLKIWGGDNLEMS--FRVWQ---C--GGEVEIAPCSHVGHLFRKSSPYTFPGGVSGIL 389
                     ||...::.|||  .||.:   |  .|........:.|...|:          :|.:
 Frog   358 ---------KILQIEDSEMSRVIRVSELSLCDLAGSERTMKTQNEGERLRE----------TGNI 403

  Fly   390 NENLAR----VALVWMDDWAKFF----FKFNKGTEEFKS-----------LNVSN-RLALKRSLN 434
            |.:|..    :.::...:.:||.    |:.:|.|..|:|           :|:|. .||...:||
 Frog   404 NTSLLTLGKCINVLKNSEKSKFQQHVPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLN 468

  Fly   435 CKSFDWYLRQVW-PQNFFPAPNKFFGRI---QPIDLTS------------TFDYQEYL-TLMKKI 482
            ...|....::|. |.....:..|.||.:   |.:.|.|            |..::..| .||:..
 Frog   469 VLKFSAIAQKVCVPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLMEDE 533

  Fly   483 NLIIKNLNPELKWKFLIKYLTENVKRIGDSMKAAKHSPYCLHKPKTNTAINQPYGQAYLQKCSLL 547
            :|:.:..|.|.......|.|.|::.:..:..||     :..|:.|.
 Frog   534 DLVEELENAEETQNVETKLLDEDLDKTLEENKA-----FISHEEKR------------------- 574

  Fly   548 INVLDEQFVIDDYGRVMTDEGICLDSFRKTSIDGE-EIVEGVRKIKMVTCGSQKPNQRWVYETDT 611
             .:||   :|:|..:.:.:|       :|..:..| :|.|.|         :|:..|.|.
 Frog   575 -KLLD---LIEDLKKKLINE-------KKEKLTLEFKIREEV---------TQEFTQYWA----- 614

  Fly   612 YHLKNIGDGTECLERSATLTREDGEDKYELF---LGPCDVRNELQK 654
               :...|..|.|.:...:..|:.|.:..:|   :|.||.|.|..|
 Frog   615 ---QREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAK 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	25/122 (20%)
rab5d	NP_001025576.1	Rab5_related	19..181	CDD:206653	24/111 (22%)