Protein Alignment Rab30 and RAB5A

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_004153.2
• Gene: RAB5A / 5868
• HGNCID: 9783
• Length: 215
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 74/203 - (36%)
• Similarity: 116/203 - (57%)
• Gaps: 11/203 - (5%)

  Fly     8 FKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQERFRSI 72
            ||:||:|.:.|||:.||.||.:|.|...|.:|||..|:.:||.::...:|.:|||||||||:.|:
Human    21 FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    73 TQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTD-RDDREIPTQIGEE 136
            ...|||.|.|.|:||||:.:.:|....:|::|:|..|:..::..|.|||.| .:.|.:..|..:.
Human    86 APMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQS 150

  Fly   137 FAKQHDMYFLETSAKEAENVERLFYEIAAELIGQARSKDGSSSAAAAAAQRQSEGSSIGLGSFSA 201
            :|..:.:.|:|||||.:.||..:|..||.:|........|::||         .|..:.| :...
Human   151 YADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSA---------RGRGVDL-TEPT 205

  Fly   202 KAAQSNCC 209
            :..::.||
Human   206 QPTRNQCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	66/160 (41%)
RAB5A	NP_004153.2	Rab5_related	20..182	CDD:206653	66/160 (41%)
		Switch 1. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	44..56		5/11 (45%)
		Switch 2. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	77..93		9/15 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		8/43 (19%)