Protein Alignment Rab30 and RAB3A

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 76/190 - (40%)
• Similarity: 121/190 - (63%)
• Gaps: 8/190 - (4%)

  Fly     2 EDYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQ 66
            :::.::|||:::||:.||||..:.|:....|.|...:|:|:||.:||:....::|||||||||||
Human    17 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQ 81

  Fly    67 ERFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYA--NSKVLKILVGNKTD-RDDRE 128
            ||:|:||.:|||.|...||:|||:.:.:|:.:.||..:|:.|:  |::||  |||||.| .|:|.
Human    82 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVL--LVGNKCDMEDERV 144

  Fly   129 IPTQIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIGQ--ARSKDGSSSAAAAAAQ 186
            :.::.|.:.|......|.|.|||:..||::.| |...::|.:  :.|.|.:..|...|.|
Human   145 VSSERGRQLADHLGFEFFEASAKDNINVKQTF-ERLVDVICEKMSESLDTADPAVTGAKQ 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	70/168 (42%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	71/166 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/8 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		10/15 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		3/10 (30%)