DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab30 and rab30

DIOPT Version :9

Sequence 1:	NP_001245926.1	Gene:	Rab30 / 33988	FlyBaseID:	FBgn0031882	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001002750.1	Gene:	rab30 / 437023	ZFINID:	ZDB-GENE-040718-250	Length:	201	Species:	Danio rerio

Alignment Length:	213	Identity:	136/213 - (63%)
Similarity:	162/213 - (76%)	Gaps:	19/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAG 65
            ||||.:||||||:|||||||||||||||||||||||||||||||||||||::|.|:|||||||||
Zfish     1 MEDYDYLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEIKGVKVKLQIWDTAG 65

  Fly    66 QERFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTD-RDDREI 129
            |||||||||||||||:||||.|||:|:.:|.|||:|||||::|||::|:.||||||.| .|.||:
Zfish    66 QERFRSITQSYYRSANALILTYDITCEDSFRCLPEWLREIEQYANNQVVTILVGNKIDLADKREV 130

  Fly   130 PTQIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIGQARSK--DGSSSAAAAAAQRQSEGS 192
            ..|..||||....|.:|||||||::|||:||.::|.|||.:|:..  |.:.|     .....||.
Zfish   131 LRQRAEEFADSQSMLYLETSAKESDNVEKLFLDLACELIREAKQNTLDNNDS-----TPMPGEGK 190

  Fly   193 SIG-LGSFSAKAAQSNCC 209
            :|. ||          ||
Zfish   191 NINYLG----------CC 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_001245926.1	Rab30	1..168	CDD:133314	124/167 (74%)
rab30	NP_001002750.1	Rab30	1..169	CDD:133314	124/167 (74%)
rab30	NP_001002750.1	RAB	8..170	CDD:197555	120/161 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596632
Domainoid	1	1.000	243	1.000	Domainoid score	I2160
eggNOG	1	0.900	-	-		E1_KOG0095
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22815
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3080
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	1	1.000	-	-		FOG0007336
OrthoInspector	1	1.000	-	-		oto39667
orthoMCL	1	0.900	-	-		OOG6_110019
Panther	1	1.100	-	-	LDO	PTHR47977
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4448
SonicParanoid	1	1.000	-	-		X5453
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790