Protein Alignment Rab30 and RAB8A

DIOPT Version :10

• Sequence 1: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 84/196 - (42%)
• Similarity: 133/196 - (67%)
• Gaps: 7/196 - (3%)

  Fly     4 YKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQER 68
            |.:|||::|:|::||||||::.||::..|.....:|||:||.|:|:|::|::|||||||||||||
Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69

  Fly    69 FRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTD-RDDREIPTQ 132
            ||:||.:|||.|..::|||||:.:.:||.:.:|:|.|:|:|::.|.|:::|||.| .|.|::..:
Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134

  Fly   133 IGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIG------QARSKDGSSSAAAAAAQRQSEG 191
            .||:.|..:.:.|:|||||...|||..|:.:|.::..      :..|..||:........:|...
Human   135 RGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQKRS 199

  Fly   192 S 192
            |
Human   200 S 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	79/164 (48%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	78/165 (47%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)