DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab30 and rab-30

DIOPT Version :9

Sequence 1:	NP_001245926.1	Gene:	Rab30 / 33988	FlyBaseID:	FBgn0031882	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_499328.1	Gene:	rab-30 / 176476	WormBaseID:	WBGene00004282	Length:	216	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	136/214 - (63%)
Similarity:	164/214 - (76%)	Gaps:	7/214 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAG 65
            |||||:|||:|||||||||||||||:||||:|||||.||||||||||||:|..:|||||||||||
Worm     1 MEDYKYLFKVVLVGNAGVGKTCLVRKFTQGIFPPGQSATIGVDFMIKTVKVGNDKIKLQIWDTAG 65

  Fly    66 QERFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTDR-DDREI 129
            |||||||||||||||||::||||:||||:|||||:||.||:.|||.:|||||||||.|: |:||:
Worm    66 QERFRSITQSYYRSAHAIVLVYDVSCQPSFDCLPEWLGEIESYANRRVLKILVGNKVDKGDEREV 130

  Fly   130 PTQIGEEFA--KQHDMYFLETSAKEAENVERLFYEIAAELIGQARSKDG--SSSAAAAAAQRQSE 190
            |.:||.:|:  .|.| |||||||.:|.||::||.::|..|....:..|.  ....|.|.....|.
Worm   131 PERIGRDFSDVNQFD-YFLETSALDATNVDQLFEQVATRLTNDMKLTDERVHQFRADATNSSSST 194

  Fly   191 GSSIGLGSFSAKAAQSNCC 209
            |..|.|.. .|:...::||
Worm   195 GGPIKLID-RAQTQLNSCC 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab30	NP_001245926.1	Rab30	1..168	CDD:133314	125/169 (74%)
rab-30	NP_499328.1	P-loop_NTPase	1..170	CDD:304359	125/169 (74%)
rab-30	NP_499328.1	RAB	8..169	CDD:197555	119/161 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167740
Domainoid	1	1.000	245	1.000	Domainoid score	I1215
eggNOG	1	0.900	-	-		E1_KOG0095
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22815
Inparanoid	1	1.050	264	1.000	Inparanoid score	I1885
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	1	1.000	-	-		FOG0007336
OrthoInspector	1	1.000	-	-		oto19118
orthoMCL	1	0.900	-	-		OOG6_110019
Panther	1	1.100	-	-	LDO	PTHR47977
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4448
SonicParanoid	1	1.000	-	-		X5453
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.830