DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MME1 and YMC2

DIOPT Version :9

Sequence 1:NP_609093.1 Gene:MME1 / 33987 FlyBaseID:FBgn0031881 Length:299 Species:Drosophila melanogaster
Sequence 2:NP_009662.3 Gene:YMC2 / 852401 SGDID:S000000308 Length:329 Species:Saccharomyces cerevisiae


Alignment Length:326 Identity:104/326 - (31%)
Similarity:147/326 - (45%) Gaps:57/326 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 EEVEISTEKK---SNPV-KSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDC 62
            ::|....||:   ||.| |...||.:||:..||||.|.||.||||||..|...        .::.
Yeast    18 QKVTTPNEKRELSSNRVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTRTT--------TLEV 74

  Fly    63 AARTFRYEGFRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLFQTDDHIR---------------- 111
            .....:.||...||:|...||:||....:|.|.|..|.||.||..:..:                
Yeast    75 LRNLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNT 139

  Fly   112 LTYPQIFAAGALAGVCSALVTVPTDRIKVLLQTQTVSNGPLLYNGTIDTAAKLYRQGGI-RSLFK 175
            |...|.:..|...||.::.:..|.::|::.|||||.:.|...:.|..|...||..|||: |.|| 
Yeast   140 LPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQTQTSNGGDREFKGPWDCIKKLKAQGGLMRGLF- 203

  Fly   176 GTCACILRDSPT--------GFYFVTYEFL--QELARKKSANGKISTTSTILSGGTAGIVFWTLA 230
                      ||        |.||:.||.|  :|:....:.| :|......|.|..:|.:.|...
Yeast   204 ----------PTMIRAGHGLGTYFLVYEALVAREIGTGLTRN-EIPPWKLCLFGAFSGTMLWLTV 257

  Fly   231 VPFDVLKSRLQS----APEGTYKHGIRSVFRNLMATEGPKALFRGILPILLRAFPSTAAVFFGVE 291
            .|.||:||.:|:    .|:  ||:.|..|.:.:.|.||.:|.|:|..|.::|:.|...|.|...|
Yeast   258 YPLDVVKSIIQNDDLRKPK--YKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATFLTFE 320

  Fly   292 L 292
            |
Yeast   321 L 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MME1NP_609093.1 Mito_carr 10..107 CDD:278578 40/100 (40%)
Mito_carr 111..205 CDD:278578 32/120 (27%)
Mito_carr 208..297 CDD:278578 29/89 (33%)
YMC2NP_009662.3 Mito_carr 34..120 CDD:395101 37/93 (40%)
Mito_carr 138..223 CDD:395101 30/95 (32%)
Mito_carr 235..328 CDD:395101 30/90 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0758
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54095
OrthoFinder 1 1.000 - - FOG0000326
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_101471
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1756
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.750

Return to query results.
Submit another query.