DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MME1 and slc25a20l

DIOPT Version :9

Sequence 1:	NP_609093.1	Gene:	MME1 / 33987	FlyBaseID:	FBgn0031881	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_031746643.1	Gene:	slc25a20l / 779503	XenbaseID:	XB-GENE-5944561	Length:	303	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	134/293 - (45%)
Similarity:	185/293 - (63%)	Gaps:	4/293 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 STEKKSNPVKSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEG 71
            |..:.:.|||:.||||:||||.:|.|.|||||||.|||.|:|..||.|.|...:.|.::....||
Frog     5 SKTQTAPPVKNVIAGGIGGMCLILAGQPLDTIKVNLQTQPSPALGQQPLYNSTLHCFSKIIAREG 69

  Fly    72 FRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLFQTDDHIRLTYPQIFAAGALAGVCSALVTVPTD 136
            .||.|||:.|||..||||.::.|..:..||.|.||.....|...|:|.||.|||:.|.::..|.:
Frog    70 IRGLYRGMGAPLAVVTPIMSITFVGFGLGKSLQQTSPDSILRSWQVFVAGMLAGLSSTVLMAPGE 134

  Fly   137 RIKVLLQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSP-TGFYFVTYEFLQEL 200
            |||.|||.|:|:. ...:.|.:|.|..|||:.|||.|::||...::||.| ||.||::||:::|.
Frog   135 RIKCLLQVQSVTL-KKTFQGPLDCAQTLYRELGIRGLYRGTLLTLIRDVPSTGVYFMSYEWMKEK 198

  Fly   201 AR-KKSANGKISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIRSVFRNLMATEG 264
            .| ::|:..::..|..:|:||.||:..|.:|:|.||||||.|:|||..||: |..|.|.::.:||
Frog   199 MRGERSSARELRATEILLAGGVAGMCNWLVAIPADVLKSRFQTAPENHYKN-ILEVLREVLHSEG 262

  Fly   265 PKALFRGILPILLRAFPSTAAVFFGVELTNDLL 297
            |..|:||....:|||||:.||.|.|.|.:...|
Frog   263 PCGLYRGFTAAMLRAFPANAACFLGFEASMSFL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MME1	NP_609093.1	Mito_carr	10..107	CDD:278578	49/96 (51%)
		Mito_carr	111..205	CDD:278578	41/95 (43%)
		Mito_carr	208..297	CDD:278578	40/88 (45%)
slc25a20l	XP_031746643.1	Mito_carr	8..105	CDD:395101	49/96 (51%)
		Mito_carr	110..201	CDD:395101	40/91 (44%)
		Mito_carr	215..295	CDD:395101	39/80 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6625
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2219
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1072378at2759
OrthoFinder	1	1.000	-	-		FOG0000326
OrthoInspector	1	1.000	-	-		mtm9345
Panther	1	1.100	-	-	O	PTHR45624
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2353
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160