DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MME1 and slc25a24

DIOPT Version :10

Sequence 1:NP_609093.1 Gene:MME1 / 33987 FlyBaseID:FBgn0031881 Length:299 Species:Drosophila melanogaster
Sequence 2:NP_001004606.1 Gene:slc25a24 / 447867 ZFINID:ZDB-GENE-040912-183 Length:477 Species:Danio rerio


Alignment Length:303 Identity:75/303 - (24%)
Similarity:128/303 - (42%) Gaps:49/303 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 EISTEKKSNPV--KSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTF 67
            |.:.|:|:..:  |...||||.|..:.....|||.:||.:|.     .........:::...:..
Zfish   184 EFTEEEKTTGMWWKQLAAGGVAGAVSRTGTAPLDRMKVFMQV-----HSSKTNKISLVNGFKQMI 243

  Fly    68 RYEGFRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLFQTD-----DHIRLTYPQIFAAGALAGVC 127
            :..|....:||....::.:.|..|:.|..|...|:|...|     .|.|      |.||:|||..
Zfish   244 KEGGVASLWRGNGVNVIKIAPETAIKFMAYEQYKKLLSKDGGKVQSHER------FMAGSLAGAT 302

  Fly   128 SALVTVPTDRIKVLLQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSP-TGFYF 191
            :.....|.:.:|..|..:....    |:|..|.|.|:.|:.|:::.:||....||...| .|...
Zfish   303 AQTAIYPMEVMKTRLTLRKTGQ----YSGMFDCAKKILRKEGVKAFYKGYVPNILGIIPYAGIDL 363

  Fly   192 VTYEFLQEL----ARKKSAN---------GKISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQ-- 241
            ..||.|:..    ..|.:||         |.||:|...|:           :.|..::::|:|  
Zfish   364 AVYETLKNTWLSHYAKDTANPGVLVLLGCGTISSTCGQLA-----------SYPLALIRTRMQAM 417

  Fly   242 SAPEGTYKHGIRSVFRNLMATEGPKALFRGILPILLRAFPSTA 284
            ::.||:.:..:..:.:.:|..||...|:|||||..::..|:.:
Zfish   418 ASMEGSEQVSMSKLVKKIMQKEGFFGLYRGILPNFMKVIPAVS 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MME1NP_609093.1 Mito_carr 10..107 CDD:395101 22/98 (22%)
Mito_carr 111..205 CDD:395101 27/98 (28%)
Mito_carr 208..297 CDD:395101 20/79 (25%)
slc25a24NP_001004606.1 Regulatory N-terminal domain. /evidence=ECO:0000250|UniProtKB:Q6NUK1 1..174
FRQ1 22..152 CDD:444056
Linker region. /evidence=ECO:0000250|UniProtKB:Q6NUK1 160..169
C-terminal transmembrane transporter domain. /evidence=ECO:0000250|UniProtKB:Q6NUK1 175..477 75/303 (25%)
PTZ00169 201..454 CDD:240302 70/278 (25%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.