DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MME1 and SPAC4G9.20c

DIOPT Version :9

Sequence 1:	NP_609093.1	Gene:	MME1 / 33987	FlyBaseID:	FBgn0031881	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_593701.2	Gene:	SPAC4G9.20c / 2543680	PomBaseID:	SPAC4G9.20c	Length:	298	Species:	Schizosaccharomyces pombe

Alignment Length:	294	Identity:	91/294 - (30%)
Similarity:	147/294 - (50%)	Gaps:	15/294 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SNPVKSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEGFRGFY 76
            |...|.|:||..||:..||||.|.|.:|||||:.    ....|.|...:||..:..:.||...||
pombe    11 SQSTKDFLAGVSGGVAQVLVGQPFDCVKVRLQSQ----SNVSPIYNNALDCVKKISKNEGLAAFY 71

  Fly    77 RGISAPLVGVTPIYAVDFAVYAAGKRLFQTDDHIRLTYPQIFAAGALAGVCSALVTVPTDRIKVL 141
            :|...||:|:....::.|..:...||.|..|. ..:|.||.:.:||::|:.::.:..|.:.:::.
pombe    72 KGTVLPLLGIGFCVSIQFTTFEYCKRFFSRDG-TPVTMPQYYVSGAISGLANSFLVGPVEHVRIR 135

  Fly   142 LQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDS-PTGFYFVTYEFLQELARKKS 205
            ||.||..|  :||:|..|...|:..|.|:..:.||......|:: ..|.||:.||.|.:....|.
pombe   136 LQIQTGKN--VLYHGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFLAYEALVKNTMAKH 198

  Fly   206 ANGKISTT---STILSGGTAGIVFWTLAVPFDVLKSRLQS---APEGTYKHGIRSVFRNLMATEG 264
            .....|.|   ...:.|..||...|..|.|||::||::|:   ..:.|||:..:.. :.:....|
pombe   199 HLTDRSQTPGWKLCVFGAGAGYAMWLAAYPFDIVKSKIQTDGFLSKATYKNSWQCA-KGIYTKAG 262

  Fly   265 PKALFRGILPILLRAFPSTAAVFFGVELTNDLLK 298
            .:..:||.:|:|:||.|:.|..|:..|..:..::
pombe   263 LRGFYRGFVPVLVRAAPANAVTFYVYETVSQHIR 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MME1	NP_609093.1	Mito_carr	10..107	CDD:278578	34/94 (36%)
		Mito_carr	111..205	CDD:278578	28/94 (30%)
		Mito_carr	208..297	CDD:278578	27/94 (29%)
SPAC4G9.20c	NP_593701.2	PTZ00169	15..286	CDD:240302	88/278 (32%)
		Mito_carr	15..103	CDD:278578	33/91 (36%)
		Mito_carr	105..198	CDD:278578	28/94 (30%)
		Mito_carr	204..297	CDD:278578	27/94 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I2789
eggNOG	1	0.900	-	-		E1_KOG0758
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1238
OMA	1	1.010	-	-		QHG54095
OrthoFinder	1	1.000	-	-		FOG0000326
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101471
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1756
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800