DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MME1 and Slc25a20

DIOPT Version :9

Sequence 1:	NP_609093.1	Gene:	MME1 / 33987	FlyBaseID:	FBgn0031881	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_446417.2	Gene:	Slc25a20 / 117035	RGDID:	621443	Length:	301	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	142/291 - (48%)
Similarity:	193/291 - (66%)	Gaps:	5/291 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KKSNPVKSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEGFRG 74
            |..:|:|:.:|||.||:|.|.|||||||:||||||.|...|||||.|.|.|||..:|...||..|
  Rat     6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITG 70

  Fly    75 FYRGISAPLVGVTPIYAVDFAVYAAGKRLFQTDDHIRLTYPQIFAAGALAGVCSALVTVPTDRIK 139
            .|||::||::||||::||.|..:..||||.|......|||||:|.||.|:||.:..:..|.:|||
  Rat    71 LYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIK 135

  Fly   140 VLLQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSP-TGFYFVTYEFLQEL--A 201
            .|||.| .|:|...|:||:|.|.|||::.|||..:|||...::||.| :|.||:|||:|:.|  .
  Rat   136 CLLQIQ-ASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTP 199

  Fly   202 RKKSANGKISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIRSVFRNLMATEGPK 266
            :.||.: .:|....:::||.|||..|.:|:|.||||||.|:||.|.|.:|.|.|.|.|:..||..
  Rat   200 QGKSVH-DLSVPRVLVAGGFAGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVT 263

  Fly   267 ALFRGILPILLRAFPSTAAVFFGVELTNDLL 297
            :|::|...:::||||:.||.|.|.|:...:|
  Rat   264 SLYKGFNAVMIRAFPANAACFLGFEIAMKIL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MME1	NP_609093.1	Mito_carr	10..107	CDD:278578	55/96 (57%)
		Mito_carr	111..205	CDD:278578	46/96 (48%)
		Mito_carr	208..297	CDD:278578	38/88 (43%)
Slc25a20	NP_446417.2	Mito_carr	6..103	CDD:278578	55/96 (57%)
		Solcar 1	8..99		51/90 (57%)
		PTZ00169	11..277	CDD:240302	131/267 (49%)
		Mito_carr	106..198	CDD:278578	46/92 (50%)
		Solcar 2	108..196		45/88 (51%)
		Mito_carr	206..294	CDD:278578	38/87 (44%)
		Solcar 3	207..293		38/85 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I4930
eggNOG	1	0.900	-	-		E1_KOG0758
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	328	1.000	Inparanoid score	I2381
OMA	1	1.010	-	-		QHG54095
OrthoDB	1	1.010	-	-		D1072378at2759
OrthoFinder	1	1.000	-	-		FOG0000326
OrthoInspector	1	1.000	-	-		otm44491
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45624
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2353
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940