DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gart and ADE8

DIOPT Version :9

Sequence 1:	NP_001285698.1	Gene:	Gart / 33986	FlyBaseID:	FBgn0000053	Length:	1353	Species:	Drosophila melanogaster
Sequence 2:	NP_010696.3	Gene:	ADE8 / 852017	SGDID:	S000002816	Length:	214	Species:	Saccharomyces cerevisiae

Alignment Length:	202	Identity:	68/202 - (33%)
Similarity:	107/202 - (52%)	Gaps:	21/202 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1155 RVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKTGVLGLQRATQAGIPSLV--------- 1210
            |:.|||||:||||||||||.:....|..|.:|.|||:.....||.||....||:.|
Yeast     3 RIVVLISGSGSNLQALIDAQKQGQLGEDAHIVSVISSSKKAYGLTRAADNNIPTKVCSLYPYTKG 67

  Fly  1211 ISHKDFA----SREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRG-RLVNIHPSLLPKY 1270
            |:.:|.|    :|..::.:|.:.:...:.|:|..||::.:|.:.|:.:.:. .::|:||:|...:
Yeast    68 IAKEDKAARAKARSQFENDLAKLVLEEKPDVIICAGWLLILGSTFLSQLQSVPILNLHPALPGCF 132

  Fly  1271 PG-LHVQKQALEAGEKE-----SGCTVHFVDEGVDTGAIIVQAAVPILPDDDE-DSLTQRIHKAE 1328
            .| .|..:.|....:.|     :||.||:|.|.||.|..:|...:.|:|.::. :...||:|.||
Yeast   133 DGTTHAIEMAWRKCQDENKPLTAGCMVHYVIEEVDKGEPLVVKKLEIIPGEETLEQYEQRVHDAE 197

  Fly  1329 HWAFPRA 1335
            |.|...|
Yeast   198 HIAIVEA 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gart	NP_001285698.1	PRK00885	4..433	CDD:234856
		GARS_N	4..107	CDD:280931
		GARS_A	108..301	CDD:279419
		GARS_C	337..430	CDD:280930
		PRK05385	442..752	CDD:235439
		PurM	485..752	CDD:100032
		PRK05385	836..1122	CDD:235439
		PurM	840..1123	CDD:100032
		FMT_core_GART	1155..1339	CDD:187714	68/202 (34%)
ADE8	NP_010696.3	Formyl_trans_N	2..205	CDD:395436	68/202 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I1688
eggNOG	1	0.900	-	-		E1_COG0299
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S947
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.760