Protein Alignment uif and clec-41

DIOPT Version :10

• Sequence 1: NP_001162899.1
• Gene: uif / 33983
• FlyBaseID: FBgn0031879
• Length: 3589
• Species: Drosophila melanogaster
• Sequence 2: NP_506271.1
• Gene: clec-41 / 179797
• WormBaseID: WBGene00007153
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 130/568 - (22%)
• Similarity: 197/568 - (34%)
• Gaps: 180/568 - (31%)

  Fly    18 SLLLLNLLHLIGADEAFSCPNGWELRGLN--CYKYFN--IKHSWDKSAELCRRYGAELVAIDSYA 78
            |.|||.:|..:.||   :||.|:.....:  |.|...  .||| |.:|. |..||..|:::.:..
 Worm     5 STLLLAILVAVSAD---TCPAGFTALSTSKKCVKLITDVAKHS-DATAN-CSSYGGHLISVQNAI 64

  Fly    79 ENNETLAIARASDPNQRASDKYWLGL-ASL---------DDLRTNTLESASGALISQYSGYWSLH 133
            :||..|.:|..|      ...||||: .||         ||...|    |.|     |:|: :..
 Worm    65 DNNAYLQLAAVS------VTPYWLGIKCSLSGNPASCQWDDQSGN----AGG-----YNGF-APG 113

  Fly   134 QPNAESGECV----AAAFAGKSQSWDLGT------CE------------------------SLLP 164
            .|..|.|.||    :.:||||..|.|..|      ||                        |.||
 Worm   114 YPLVEVGNCVYVPTSGSFAGKWLSGDCNTMSLNFICETAPTSPITDTCSFQYNGNCYYPSLSALP 178

  Fly   165 -----FMCRAQACPQ-GSLH------------------------CAN------------------ 181
                 |.|: |||.. .|:|                        .||
 Worm   179 KQDAQFSCQ-QACGNLVSIHSIEENNYVQSLFTTNAPTYIRIGAVANNQNSNSWIDGTSWNYDNI 242

  Fly   182 -------GKCINQAFK-------------CDGS----------DDCGDGTDELDCPAQC--HYHM 214
                   |.|.:.|..             ||.|          ..||..:.....|.||  ...|
 Worm   243 GYSNINLGMCWSMALSNDIVSTGKWISSYCDTSLPFVCKRKVGTQCGTTSGPTQTPGQCTSPMFM 307

  Fly   215 QSGGDVIETPNYPHKY-GALSKCKWTLEGPLGSNIILQFQDFETEKTFDTVQILVGGRTEDKSVS 278
            .:.|. ..:|::|:.| |..:.|.:.|:.|:||.:.::|.....:   ....|.:..|.|| :..
 Worm   308 DNSGR-FYSPSWPYSYIGEQNPCNYILDTPVGSLVQIRFPVMNLD---SQASISIYSRIED-TTP 367

  Fly   279 LATLSGKQDLTTQPFVSASNFMIVKF-TTDGSVERKGFRATWKTEAK------------------ 324
            |..|.| ...:.|.:.|.:|.|.|.| ....:....|....|:.:.|
 Worm   368 LVVLQG-NSASNQWYTSTTNTMKVVFRPCIANCPNDGVNYRWEADFKPSTDVTQPPVTVTPNPNN 431

  Fly   325 --NCGGTLKATLQRQILTSPNYPKQYPGGLECLYVIKAQPGRIISIEVDDLDIADGRDFLMIRDG 387
              .|..|:  .:....:::||||..||..|.|:|.:....|..|:::...:|.....|.:.:.||
 Worm   432 PSGCNSTI--LVAPGSISTPNYPNYYPNFLLCMYHLSTTGGYRINLDFGAIDTEQCCDIIEVHDG 494

  Fly   388 ESPMSRTIAKLTGKTAQNNRVIISTGNALYLYFKSSLGEAGKGFSLRY 435
            ....|..:..::|....:.:...|:.|::.:.|.:.....|.|||..:
 Worm   495 PLLGSPKLGIVSGTWPAHAKTYQSSSNSMLVTFSTDSSGQGSGFSANF 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uif	NP_001162899.1	CLECT	36..167	CDD:214480	50/183 (27%)
		LDLa	172..206	CDD:238060	13/106 (12%)
		CUB	220..319	CDD:238001	24/100 (24%)
		CUB	326..435	CDD:238001	26/108 (24%)
		CUB	439..550	CDD:238001
		PHA02927	<568..733	CDD:222943
		CCP	675..731	CDD:153056
		PHA02639	697..>834	CDD:165022
		FA58C	833..976	CDD:330301
		FXa_inhibition	988..>1016	CDD:464251
		CCP	1051..1106	CDD:153056
		FA58C	1303..1443	CDD:330301
		HYR	1463..1547	CDD:460572
		HYR	1548..1631	CDD:460572
		Ephrin_rec_like	1862..1909	CDD:429604
		Ephrin_rec_like	1916..1966	CDD:429604
		Ephrin_rec_like	1973..2020	CDD:429604
		EGF	2025..2055	CDD:394967
		EGF_CA	2059..2095	CDD:238011
		EGF_CA	2138..2176	CDD:238011
		EGF_CA	2178..2214	CDD:238011
		EGF_CA	2253..2289	CDD:238011
		EGF_CA	2292..2327	CDD:238011
		EGF_CA	2369..2405	CDD:238011
		EGF_CA	2411..2444	CDD:238011
		EGF_CA	2486..2520	CDD:238011
		EGF_CA	2522..2557	CDD:238011
		LamG	2590..2735	CDD:473984
		HYR	2799..2877	CDD:460572
		Ephrin_rec_like	3149..3200	CDD:429604
		Ephrin_rec_like	3207..3254	CDD:429604
		Ephrin_rec_like	3268..3307	CDD:429604
		Ephrin_rec_like	3315..3362	CDD:429604
clec-41	NP_506271.1	CLECT	20..150	CDD:214480	44/147 (30%)
		CLECT	163..281	CDD:214480	18/118 (15%)
		CUB	301..393	CDD:238001	25/97 (26%)
		CUB	444..542	CDD:214483	24/97 (25%)